Introduction to Antimicrobial Stewardship Programmes (ASPs) 

Antimicrobial stewardship (AMS) is a coherent set of actions that promote the optimal use of antimicrobials in a way that ensures sustainable access to effective therapy for all in need.ASPs aim to improve patient outcomes and safety and address inappropriate use of antimicrobials. Core elements identified in successful ASPs include leadership commitment, prescriber accountability, drug expertise, and education of clinicians and patients, among others. The general framework of an ASP has ideally three components:1


Antimicrobial Stewardship Programmes

1. There are system prerequisites that must be met before  implementation (e.g. presence of guidelines, AMS team, adequate diagnostic, human and IT resources) 


2. What the AMS team wants to improve must be clearly  defined (recommendations on apporpriate use at the patient level, eg. duration of treatment compliant with guidelines) 


3. How the AMS team will achieve these goals must be planned, i.e. the improvement strategies that will be chosen and tailored based on the identified determinants and problems and performed by the team at the professional or institutional level


Antimicrobial Stewardship: The Key Topics

Hear Mark Gilchrist, Consultant Pharmacist Infectious Diseases, Imperial College Healthcare NHS Trust discuss key topics surrounding Antimicrobial Stewardship.

What is antimicrobial stewardship and why is it important?


How are the antimicrobial stewardship programs implemented and what are the main goals? 


How is the clinical and economic impact of an antimicrobial stewardship program measured?


How can Pfizer support?

Delivering an Antimicrobial Stewardship Programme is a multi staged process requiring a coordinated response from a range of healthcare professionals. To support with this, Pfizer have created an Antimicrobial Stewardship Toolkit for healthcare professionals looking to enhance their antimicrobial stewardship capabilities. The AMS toolkit contains a variety of resources designed to offer advice, suggestions and tips for implementing and maintaining AMS programmes within the secondary healthcare setting.

To access these resources please visit our Educational Resources Page

AMS Lead Guide

AMS Lead Resource Pack - 'At a Glance'

Leading an AMS programme is a multi-faceted process requiring a coordinated response that engages colleagues and supports their active involvement. The items within this pack are designed to help you and your AMS Champions deliver excellent and consistent patient care through collaboration between all members of the hospital team.

AMS Champion Resource Pack

AMS Champion Resource Pack - 'At a Glance'

As an AMS Champion you play a key role in engaging with colleagues and supporting their active involvement with Antimicrobial Stewardship. The items within this pack are designed to help AMS Champions develop excellent and consistent patient care through collaboration with all members of the hospital team.



  1. Mendelson M, et al. How to start an antimicrobial stewardship programme in a hospital. Clin Microbiol & Infect. 2019 [Article in press].
  2. Nathwani D, et al. Value of hospital antimicrobial stewardship programs [ASPs]: a systematic review. Antimicrob Resist Infect Control. 2019;8:35.

Prescribing Information

Zavicefta▼ (ceftazidime avibactam)
ZAVICEFTA® 2 g/0.5 g Powder for Concentrate for Solution for Infusion – SPC
Legal category: POM. Basic NHS price: 10 vial pack £857.00.

Cresemba (isavuconazole)
Cresemba 100mg hard capsules – SPC
Legal Category: POM. Basic NHS Cost:14 caps pack £599.28
Cresemba 200mg powder for concentrate for solution for infusion – SPC
Legal Category: POM Basic NHS Cost: 1 vial pack £297.84
Zinforo (ceftaroline fosamil)
Zinforo® 600 mg powder for concentrate for solution for infusion - SPC
Legal category: POM.  Basic NHS cost: 10 vial pack £375.00

PP-AIP-GBR-0571.  December 2020