Heart with magnifying glass revealing a maze in a ventricle, alongside text reading 'ATTR-CM suspect & detect, uncover the clues for diagnosis'

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Diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM)


The diagnosis of ATTR-CM is often delayed or missed, resulting in an underdiagnosed* cause of heart failure with preserved ejection fraction (HFpEF).1,2

*In two studies, wild-type ATTR deposits were identified in the hearts of 1317% of older patients with HFpEF.1,2

  • In an ex-US study of 120 HFpEF patients 60 years or older, wild-type ATTR was confirmed in 13% (13.3%; 95% CI: 7.219.5) of the patients1
  • In a US study of 441 autopsied patients, 109 of whom had HFpEF, cardiac wild-type ATTR deposits were found in 17% of the patients2