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AboutAboutConjugate TechnologyPneumococcal DiseaseDosing & AdministrationDosing & AdministrationDosing, Administration & StoragePrevious Pneumococcal VxClinical Trial ProgrammeClinical Evidence & SafetyClinical Trial ProgrammeSafety ProfilePrivate Vaccination Service Private Vaccination ServiceIdentifying Those at Increased Risk of Pneumococcal Pneumonia

The content of this site is based on the Prescribing Information for APEXXNAR®▼ (pneumococcal polysaccharide conjugate vaccine (20-valent, adsorbed)) for Great Britain. The Prescribing Information for Great Britain can be found here. Prescribing Information for Prevenar 13® (pneumococcal polysaccharide conjugate vaccine (13-valent, adsorbed)) can be found here.

Conjugate Technology

APEXXNAR is built on the foundations of Prevenar 13® (pneumococcal polysaccharide conjugate vaccine (13-valent, adsorbed)).1,2 APEXXNAR and Prevenar 13 are both conjugate vaccines.1,2



What is a conjugate vaccine?


The information in the diagram below is general vaccine information and not all information is specific to pneumococcal vaccines

How does APEXXNAR work?
APEXXNAR adds 7 serotypes to Prevenar 13 to deliver the broadest serotype coverage available for adults from a pneumococcal conjugate vaccine in one dose.1,2
...
Clinical Trial Programme

The safety profile and immunogenicity of APEXXNAR was evaluated in 4,552 adults in 6 clinical trials1 

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Who is at risk?

Watch videos about chronic conditions that can put your patients at increased risk of pneumococcal disease

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Key Information on APEXXNAR

Key information about dosing, administration and storage for APEXXNAR1

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References:
  1. APEXXNAR (Pneumococcal polysaccharide conjugate vaccine [20-valent, adsorbed]). Summary of Product Characteristics GB.
  2. Prevenar 13 (Pneumococcal polysaccharide conjugate vaccine [13-valent, adsorbed]). Summary of Product Characteristics GB.
  3. Froes F, Roche N, Blasi F. Pneumococcal vaccination and chronic respiratory diseases. Int J Chron Obstruct Pulmon Dis. 2017 Dec 5;12:3457-3468. doi: 10.2147/COPD S140378. PMID: 29255353; PMCID: PMC5723118.
  4. Pollard AJ, Perrett KP, and Beverley PC. Maintaining protection against invasive bacteria with protein–polysaccharide conjugate vaccines. Nature Reviews Immunology. 2009;9:213-220.
PP-PNR-GBR-0151. March 2024

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

for MHRA Yellow Card in Google Play or Apple App Store

 

Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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