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AboutAboutConjugate TechnologyPneumococcal DiseaseDosing & AdministrationDosing & AdministrationDosing, Administration & StoragePrevious pneumococcal VxClinical Trial ProgrammeClinical Evidence & SafetyClinical Trial programmeSafety ProfilePrivate Vaccination Service Private Vaccination ServiceIdentifying Those at Increased Risk of Pneumococcal PneumoniaSupport & ResourcesSupport & ResourcesVideosMaterials

Prescribing Information for APEXXNAR® (pneumococcal polysaccharide conjugate vaccine (20-valent, adsorbed)) can be found here and for Prevenar 13® (pneumococcal polysaccharide conjugate vaccine (13-valent, adsorbed)) can be found here. Adverse event reporting information can be found at the bottom of the page

Pneumococcal Disease

What is pneumonia?

Pneumonia is swelling (inflammation) of the tissue in one or both lungs, usually caused by a bacterial or viral infection.1,2 Pneumonia can affect anyone, although some groups are at higher risk1,2

Symptoms of pneumonia

One of the most common symptoms of pneumonia is a cough, which can be dry or mucus producing (yellow, green, brownish or blood-stained).1,2

Other common symptoms include difficulty breathing, rapid heartbeat, fever, generally feeling unwell, sweating and shivering, loss of appetite, and chest pain.1,2

Mild cases can usually be treated at home, but may leave sufferers with a persistent cough for up to 6 weeks and lasting fatigue3. Severe cases may require hospitalisation due to a higher risk of developing serious complications.1,3

Causes of pneumonia

Pneumonia is usually caused by bacteria or viruses. It can also be caused by fungal infections or aspiration of food.1,2
 
Streptococcus pneumoniae is the most common bacterial cause of pneumonia.2,6 

  • In adults aged 50 years and older, Streptococcus pneumoniae infections are responsible for approximately 36% of all hospitalised cases of community-acquired pneumonia (CAP)7


† 36% of patients = 861 patients hospitalised with pneumococcal CAP out of 2412 patients hospitalised with all cause CAP

Example

About APEXXNAR

Learn about Conjugate Vaccine Technology

 

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Clinical Trial Programme

The safety profile and immunogenicity of APEXXNAR was evaluated in 4,552 adults in 6 clinical trials8

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Key Information on APEXXNAR

Key information about dosing, administration and storage for APEXXNAR8
 

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References

NHS. Overview: Pneumonia. Available at https://www.nhs.uk/conditions/Pneumonia/. Last accessed June 2023.Asthma and Lung UK. Pneumonia. Available at: https://www.blf.org.uk/support-for-you/pneumonia/what-is-pneumonia. Last accessed June 2023.NHSinform. Pneumonia. Available at: https://www.nhsinform.scot/illnesses-and-conditions/lungs-and-airways/pneumonia#treating-pneumonia. Last accessed June 2023.Office of National Statistics: Deaths due to coronavirus (COVID-19) compared with deaths from influenza and pneumonia, England and Wales: deaths occurring between 1 January and 31 August 2020. Available at:      https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsduetocoronaviruscovid19comparedwithdeathsfrominfluenzaandpneumoniaenglandandwales/deathsoccurringbetween1januaryand31august2020. Last accessed June 2023.NHS Digital. Hospital Episodes Statistics for England. NHS Digital. Hospital Admitted Patient Care Activity, 2021-22. Available at: https://digital.nhs.uk/data-and-information/publications/statistical/hospital-admitted-patient-care-activity/2021-22. Last accessed June 2023UKHSA. The Green Book [published 2013; updated 2020]. Chapter 25: Pneumococcal. Available at https://www.gov.uk/government/publications/pneumococcal-the-green-book-chapter-25. Last accessed June 2023.Pick H, et al. Pneumococcal serotype trends, surveillance and risk factors in UK adult pneumonia, 2013-18.Thorax. 2020;75(1):38-49.APEXXNAR (Pneumococcal polysaccharide conjugate vaccine[20-valent,adsorbed]) Summary of Product Characteristics GB.NHSinform. Pneumococcal infections. Available at: https://www.nhsinform.scot/illnesses-and-conditions/infections-and-poisoning/pneumococcal-infections/. Last accessed June 2023.
PP-PNR-GBR-0125 June 2023

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

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Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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