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AboutAboutConjugate TechnologyPneumococcal DiseaseDosing & AdministrationDosing & AdministrationDosing, Administration & StoragePrevious Pneumococcal VxClinical Trial ProgrammeClinical Evidence & SafetyClinical Trial ProgrammeSafety ProfilePrivate Vaccination Service Private Vaccination ServiceIdentifying Those at Increased Risk of Pneumococcal Pneumonia

The content of this site is based on the Prescribing Information for APEXXNAR®▼ (pneumococcal polysaccharide conjugate vaccine (20-valent, adsorbed)) for Great Britain. The Prescribing Information for Great Britain can be found here. Prescribing Information for Prevenar 13® (pneumococcal polysaccharide conjugate vaccine (13-valent, adsorbed)) can be found here.

Dosage, administration and storageAdministering APEXXNAR1

 

  • One dose (0.5 mL) of APEXXNAR should be administered
    intramuscularly, preferably in the deltoid muscle, with care to
    avoid injection into or near nerves and blood vessels.1
 
  • APEXXNAR has a 24-month shelf life and should be stored in a
    refrigerator (2°C to 8°C). Do not freeze.
  • Once removed from the refrigerator, APEXXNAR should be used immediately.*1

 Please refer to the APEXXNAR Summary of Product Characteristics for full dosing and administration recommendations.1  Stability data indicate that the vaccine is stable for 96 hours when stored at temperatures from 8°C to 25°C, or 72 hours when stored at temperatures from 0°C to 2°C. At the end of these time periods APEXXNAR should be used or discarded.These data are intended to guide healthcare professionals in case of temporary temperature excursion only.Who is at risk?

Watch videos about chronic conditions that can put your patients at increased risk of pneumoccocal disease

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Your guide to conjugate vaccine technology

Find out about the composition of conjugate vaccines1,2

 

 How it works →  Loading

 Clinical Trial Programme

The safety profile and immunogenicity of APEXXNAR was evaluated in 4,552 adults in 6 clinical trials1
 

 See the data →Loading

References:

  1. APEXXNAR GB (Pneumococcal polysaccharide conjugate vaccine). Summary of Product Characteristics. https://www.medicines.org.uk/emc/product/13461. Last accessed February 2024.
  2. Prevenar 13 GB (Pneumococcal polysaccharide conjugate vaccine). Summary of Product Characteristics. https://www.medicines.org.uk/emc/medicine/22689. Last accessed February 2024.
PP-PNR-GBR-0153. March 2024

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

for MHRA Yellow Card in Google Play or Apple App Store

 

Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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