Prescribing Information for Bavencio® (avelumab) + axitinib aRCC click here or Bavencio® (avelumab) MCC & UC click here. Adverse event reporting information can be found at the bottom of the page.
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Merck Serono Ltd are the marketing authorisation holder for Bavencio®. This medicine is a Merck-Pfizer co-promote.
BAVENCIO® is a human IgG1 anti-PD-L1 antibody that removes the suppressive effects of PD-L1 on cytotoxic CD8+ T-cells, restoring their anti-tumour effects.1 It is licensed for the following indications:
BAVENCIO® (avelumab) in combination with axitinib is indicated for the first-line treatment of adult patients with aRCC.1
BAVENCIO® (avelumab) is indicated
as monotherapy for the first-line maintenance treatment of adult patients with locally advanced or metastatic UC who are progression-free following platinum-based chemotherapy.1
BAVENCIO® (avelumab) is indicated as monotherapy for the treatment of adult patients with mMCC.1
Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Merck Serono Limited on 0208 818 7373 (email: [email protected])
aRCC : Advanced renal cell carcinoma, IgG1 : Immunoglobulin G1, mMCC : metastatic Merkel cell carcinoma, PD-L1 : programmed death-ligand 1, UC : Urothelial carcinoma
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