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Choosing BeneFIXChoosing BeneFIXChoosing BeneFIXPersonalised dosing On-Demand Use Product InformationProduct InformationEfficacy & SafetyAdministration & StorageSupport & ResourcesSupport & ResourcesMaterialsVideosOrdering BeneFIXContact Us

For BeneFIX® (nonacog alfa) Prescribing Information for Great Britain and Northern Ireland click here.
Adverse event reporting information can be found at the bottom of the page.

Administration & StorageAdministrationBeneFIX® can be reconstituted and administered intravenously using our R2 device.1 
  • Administered by intravenous infusion after reconstitution with sterile 0.234% w/v sodium chloride solution. BeneFIX should be administered at a slow infusion rate. The rate of administration should be determined by the patient's comfort level.1
  • For further support, refer to the BeneFIX® R2 Infusion mat step-by-step guide. Download the Infusion mats here.

Request printed copies or other materials through our Contact Us page.Storage

How to store BeneFIX®:

  • Storage flexibility at room temperature (<30°C).1
  • Do not freeze.1
  • BeneFIX® has a shelf life of 2 years.1

After reconstitution:
  • The reconstituted product does not contain a preservative and should be used immediately, but no longer than 3 hours after reconstitution.1
  • Chemical and physical in-use stability has been demonstrated for 3 hours at temperatures up to 25°C.1
  • When reconstituted, the product contains polysorbate-80, which is known to increase the rate of di-(2-ethylhexyl)phthalate (DEHP) extraction from polyvinyl chloride (PVC). This should be considered during the preparation and administration of BeneFIX®.1
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Contact us for more information on ReFacto AF and download our FAQ for supply and stock related queries.

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References

BeneFIX® Summary of Product Characteristics. For Great Britain, available here. For Northern Ireland, available here.
PP-BEN-GBR-0620. July 2023

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

for MHRA Yellow Card in Google Play or Apple App Store

 

Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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