The content of this website has been produced in line with the BOSULIF®▼ (bosutinib) Summary of Product Characteristics for Great Britain and is intended for Healthcare Professionals based in Great Britain. BOSULIF▼ Prescribing Information for Great Britain and for Northern Ireland, and adverse event reporting information can be found at the bottom of the page.
Data in newly-diagnosed adult CML patients
Compared with imatinib, BOSULIF offers:1-3
*MMR (≤ 0.1% BCR-ABL1 transcripts on the international scale with ≥ 3000 ABL1 assessed).
†Adjusted for Sokal risk group (low, intermediate, high) and geographic region at time of random assignment. 95% CIs for ORs based on asymptotic Wald confidence limits.
‡p-value based on a Cochran–Mantel–Haenszel test for general association between treatment and response with stratification by Sokal risk group (low, intermediate, high) and region as determined at time of random assignment.
§MR4, ≤ 0.01% BCR-ABL1 transcripts on the international scale with ≥ 9800 ABL1 assessed; MR4.5, ≤ 0.0032% BCR-ABL1 transcripts on the international scale with ≥ 30,990 ABL1 assessed.
Compare 2013 guidelines to those published in 2020
Watch Prof. Richard Clark discuss the holistic approach to treatment decisions for patient with CML
For Great Britain
Bosulif (bosutinib) Prescribing Information - 100mg Tablets
Bosulif (bosutinib) Prescribing Information - 400mg Tablets
Bosulif (bosutinib) Prescribing Information - 500mg Tablets
For Northern Ireland
Bosulif (bosutinib) Prescribing Information
These pages are not intended for patients or for members of the general public. The healthcare professional web pages contain promotional content.
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PP-PFE-GBR-2688. December 2020