Champix® (varenicline tartrate) Prescribing Information. Adverse event reporting information can be found at the bottom of the page.
Over 12 weeks of treatment with 12-week non-treatment follow up, in 8,144 smokers with or without a diagnosis of psychiatric disorders,† EAGLES has shown that CHAMPIX (varenicline) has:
CHAMPIX was not associated with a significantly increased risk of NPS adverse events vs. placebo in smokers with or without a history of psychiatric disorders.†1.
Watch Professor Robert West discuss the EAGLES study
CHAMPIX provides significantly superior abstinence rates vs. bupropion, NRT patch (NiQuitin® 21mg, with taper) and placebo in patients with or without a history of psychiatric disorders at weeks 9-12 (p<0.001) and at weeks 9-24 (p<0.005).1
Adapted from Anthenelli RM, et al. Lancet 2016.
Based on the all-randomised patient population. ** The primary efficacy endpoint was the CO-confirmed CAR from weeks 9-12. †† The main secondary endpoint was the CO-confirmed CAR from weeks 9-24. The other secondary endpoint was the 7-day point prevalence of abstinence at each assessment visit, which yielded results consistent with the continuous abstinence rates.
Treatment types included 1mg of varenicline twice daily vs. 150mg of bupropion twice daily vs. 21mg with taper of NiQuitin®, vs. placebo. All medications were up- or down-titrated according to prescribing information. NRT treatment was for 11 weeks.
1. Anthenelli RM, et al. Lancet 2016 Apr 22. doi: 10.1016/S0140-6736(16)30272-0
Read about how Champix compares to nicotine replacement therapies.
Learn more about how using Very Brief Advice (VBA) and Brief Support and Treatment (BST) can help a smoker gain the motivation and support needed, to quit successfully.
Download support material for patients prescribed Champix.
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