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Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

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Champix® (varenicline tartrate) Prescribing Information.  Adverse event reporting information can be found at the bottom of the page.

Champix Tolerability

The tolerability of CHAMPIX has been carefully assessed.1 

What patients can expect when quitting – with or without treatment:

  • Quitting smoking may result in nicotine withdrawal syndrome, which produces a range of effects, including depressed mood2,3
  • These effects may last from a few days to more than 10 weeks2

Common symptoms of nicotine withdrawal:4

Support your patients through nicotine withdrawal with CHAMPIX

CHAMPIX has been shown to reduce cravings and withdrawal symptoms1

The most common adverse events with CHAMPIX5







Abnormal dreams




  • Nausea is mostly mild to moderate, occurs early in treatment and infrequently results in discontinuation1
  • CHAMPIX has low discontinuation rates due to adverse events, comparable to placebo (11.4% vs. 9.7%)1
  • Based on clinical trial experience to date, CHAMPIX has no clinically meaningful drug interactions1

Please refer to the Summary of Product Characteristics for further information about adverse events that have been reported during/after Champix therapy

  1. CHAMPIX Summary of Product Characteristics
  2. McEwen A et al. Manual of smoking cessation. A guide for counsellors and practitioners. 2006, Addiction Press: Blackwell Publishing.
  3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Text Revision. Washington, DC: American Psychiatric Association; 2000.
  4. West R, Shiffman S. Fast Facts. Smoking cessation. Indispensable guides to clinical practice. 2004, Oxford: Health Press.
  5. Pfizer data on file
PP-CHM-GBR-3362. June 2021

Support material for Champix patients

Download support material for patients prescribed Champix.


Champix efficacy vs NRT

Read about how Champix compares to nicotine replacement therapies.

Champix efficacy data

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PP-PFE-GBR-2688. December 2020