Information on how to access prescribing information and adverse event reporting can be found at the bottom of the page.
CRESEMBA® contains the active substance isavuconazonium sulfate. Once hydrolysed into its active form, isavuconazole, it induces fungal cell death by inhibiting the production of fungal cell membrane components.
The SECURE study was undertaken to compare the efficacy and safety of intravenous and oral formulations of isavuconazole to voriconazole for the primary treatment of invasive aspergillosis2.
The VITAL trial was undertaken to assess the efficacy and safety of isavuconazole for treatment of mucormycosis and to compare its efficacy with amphotericin B in a matched case-control analysis3.
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Dosing recommendations for CRESEMBA
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Consider CRESEMBA® for the treatment of invasive aspergillosis and mucormycosis. For further information, contact your Pfizer representative
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Prescribing Information for Cresemba (isavuconazole)
Cresemba (isavuconazole) 100mg hard capsules
Cresemba (isavuconazole) 200mg powder for concentrate for solution for infusion
Cresemba (Isavuconazole) 100mg hard capsules and Cresemba (Isavuconazole) 200mg powder for concentrate for solution for infusion
Prescribing Information for Vfend (voriconazole)
Vfend (voriconazole) 50mg film coated tablets
Vfend (voriconazole) 200mg film coated tablets
Vfend (voriconazole) 200mg powder for solution for infusion
Vfend (voriconazole) 40mg/ml powder for oral suspension
Vfend (voriconazole): 50mg film coated tablets, 200mg film coated tablets, 200mg powder for solution for infusion & 40mg/ml powder for oral suspension
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PP-PFE-GBR-2688. December 2020