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Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

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CRESEMBA® in Invasive Aspergillosis: Efficacy

In the SECURE trial, CRESEMBA demonstrated comparable efficacy to voriconazole in invasive aspergillosis*1. This allows you to prescribe CRESEMBA with confidence in your aspergillosis patients.

*The non-inferiority margin was 10% for adjusted treatment differences between CRESEMBA and voriconazole; an upper 95% CI less than 10% suggests that CRESEMBA is non-inferior to voriconazole.

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Dosing

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References:
  1. ​​​​​​​​​​​​​​​​​​​​​Maertens JA, Raad II, Marr KA, et al. Isavuconazole versus voricanazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE); a phase 3, randomised-controlled, non-inferiority trial. Lancet. 2016;387(10020):760–769.
PP-CRB-GBR-1203. August 2021

Invasive Aspergillosis (Quick Links)

Safety Profile

 CRESEMBA safety information

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PP-PFE-GBR-2688. December 2020

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