Enbrel® MyClic Pre-Filled Pen

The MyClic pre-filled pen is a simple administration device containing 25 mg or 50 mg of Enbrel. Benefits of MyClic include higher patient adherence, satisfaction and convenience, and increased ease of use, compared with a pre-filled syringe.¹

Only Enbrel offers the range of administration and dosing options with 10 mg (paediatric), 25 mg and 50 mg strengths available.^3-6 MyClic offers increased flexibility to choose the preferred delivery method for all patient types.⁵

33% of UK RA patients say that their HCPs underestimate the pain and discomfort of injected medications.⁷

Among Enbrel patients who had previously used a pre-filled syringe, the MyClic pre-filled pen was associated with:

• Higher patient satisfaction compared to the pre-filled syringe, including easiness of learning how to use the device (p<0.001) and performing the injection (p<0.001)^*8
• Significantly reduced pain at the injection site: mean VAS score 2.91 vs. 1.77 (p<0.001)^†2
• An adherence level of >95%²
• An increase from 66% to 93% in patients self-administering Enbrel²
• A decrease from 23% to 2% in patients requiring nurse assistance in primary care facilities²

MyClic does not interfere with patients’ social lives, leisure and daily activities¹

^{​​​​​​​*}In a multi-centre, open-label, randomised, parallel-design study, 421 adult patients with psoriasis were randomised to receive Enbrel 50 mg twice weekly subcutaneously for 12 weeks either as a pre-filled syringe or as a pre-filled pen. The primary outcome was patient satisfaction at week 12 with the injection device as measured on a 0–10 point Likert scale. The study was powered to demonstrate non-inferiority of a pen over a syringe for the primary endpoint.^{8​​​​​​​}

^†38 men and 66 women diagnosed with rheumatoid arthritis (56%), psoriatic arthritis (30%) and ankylosing spondylitis (14%) switched from the 50 mg pre-filled syringe to the 50 mg MyClic pre-filled pen. Patients answered questions during an interview 2 months after starting Enbrel treatment with the MyClic pre-filled pen.²

HCP=healthcare professional; JIA=juvenile idiopathic arthritis; RA=rheumatoid arthritis.

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References