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Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

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Information on how to access Enbrel® (etanercept) prescribing information and adverse event reporting can be found at the bottom of the page.

MyClic Pre-Filled Pen

​​​​​​​The MyClic pre-filled pen is a simple administration device containing 25 mg or 50 mg of Enbrel. Benefits of MyClic include higher patient adherence, satisfaction and convenience, and increased ease of use, compared with a pre-filled syringe.1

Simple | Sure | Secure2,3

MyClic: Flexible dosing options, with 25 mg strength

Only Enbrel offers the range of administration and dosing options with 10 mg (paediatric), 25 mg and 50 mg strengths available.3-6 MyClic offers increased flexibility to choose the preferred delivery method for all patient types.5

MyClic: Proven patient benefits1

33% of UK RA patients say that their HCPs underestimate the pain and discomfort of injected medications.7

Among Enbrel patients who had previously used a pre-filled syringe, the MyClic pre-filled pen was associated with:

  • Higher patient satisfaction compared to the pre-filled syringe, including easiness of learning how to use the device (p<0.001) and performing the injection (p<0.001)*8
  • Significantly reduced pain at the injection site: mean VAS score 2.91 vs. 1.77 (p<0.001)†2
  • An adherence level of >95%2
  • An increase from 66% to 93% in patients self-administering Enbrel2
  • A decrease from 23% to 2% in patients requiring nurse assistance in primary care facilities2​​​​​​​​​​​​​​

MyClic does not interfere with patients’ social lives, leisure and daily activities1

​​​​​​​*In a multi-centre, open-label, randomised, parallel-design study, 421 adult patients with psoriasis were randomised to receive Enbrel 50 mg twice weekly subcutaneously for 12 weeks either as a pre-filled syringe or as a pre-filled pen. The primary outcome was patient satisfaction at week 12 with the injection device as measured on a 0–10 point Likert scale. The study was powered to demonstrate non-inferiority of a pen over a syringe for the primary endpoint.8​​​​​​​

38 men and 66 women diagnosed with rheumatoid arthritis (56%), psoriatic arthritis (30%) and ankylosing spondylitis (14%) switched from the 50 mg pre-filled syringe to the 50 mg MyClic pre-filled pen. Patients answered questions during an interview 2 months after starting Enbrel treatment with the MyClic pre-filled pen.2​​​​​​​​​​​​​​​​​​​

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Enbrel dosing and administration

Learn more about the dosing and administration of Enbrel, across indications.

MyClic administration

Enbrel patient support

See what online support your patients have access to

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HCP=healthcare professional; JIA=juvenile idiopathic arthritis; RA=rheumatoid arthritis.

Prescribing Information

For Enbrel (etanercept) prescribing information, click here

  1. Müller-Ladner U, et al. Z Rheumatol. 2012;71:890-899.
  2. Borrás-Blasco J, et al. Expert Opin Biol Ther. 2013;13:1103-1108.
  3. Enbrel (etanercept) SmPC. 50 mg solution for injection in pre-filled pen. 
  4. Enbrel (etanercept) SmPC. 25 mg powder and solvent for solution for injection. 
  5. Enbrel (etanercept) SmPC. 25 mg solution for injection in pre-filled syringe. 
  6. Enbrel (etanercept) SmPC 10 mg solution for injection. 
  7. Pfizer Data on file. RA NarRAtive Patient Survey Banner.
  8. Paul C, et al. J Eur Acad Dermatol Venereol. 2012;26:448-455.
PP-ENB-GBR-1055. December 2021

Watch a video on how to admisiter Enbrel with the MyClic pen

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For UK Healthcare Professionals*

These pages are not intended for patients or for members of the general public. The healthcare professional web pages contain promotional content.

I confirm that I am a healthcare professional* resident in the United Kingdom.

If you select 'No', you will be redirected to where you will be able to access reference information on Pfizer's prescription medicines.

*The ABPI Code definition for healthcare professional is members of the medical, dental, pharmacy and nursing professionals and any other persons who in the course of their professional activities may administer, prescribe, purchase, recommend or supply a medicine.

PP-PFE-GBR-3863. November 2021



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