This site is intended only for healthcare professionals resident in the United Kingdom

Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

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Information on how to access Fragmin® (dalteparin sodium) prescribing information and adverse event reporting can be found at the bottom of the page.

Monitoring anti-Xa levels

​​​​​​​Not routinely required, but should be considered for specific patients including those with renal faliure1

Some patient populations, including those with renal failure, will require monitoring of anti-Xa levels when using Fragmin1

The Need:

Monitoring of anti-Xa levels in patients using Fragmin is not usually required but should be considered for specific patient populations such as paediatrics, those with renal failure, those who are very thin or morbidly obese, pregnant or at increased risk for bleeding or rethrombosis1

​​​​​​​Patients with severely disturbed hepatic function may need a reduction in dosage and should be monitored accordingly1

Haemodialysis:

Patients undergoing chronic haemodialysis with Fragmin need as a rule fewer dosage adjustments and as a result fewer controls of anti-Xa levels. Patients undergoing acute haemodialysis may be more unstable and should have a more comprehensive monitoring of anti-Xa levels2

Renally Impaired Patients

Find out more

Fragmin Tolerability

Find out more

Fragmin Guidelines

View guidelines

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in Google Play or Apple App Store

Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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PP-PFE-GBR-2688. December 2020

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