Information on how to access Fragmin® (dalteparin sodium) prescribing information and adverse event reporting can be found at the bottom of the page.
The risk of VTE in orthopaedic surgery is high in comparison with other surgical disciplines, with associated implications for cost and recovery time1,2
Without thromboprophylaxis, the risk of DVT in TKR patients has been documented between 41%–85%
The risk of VTE in THR patients has been assessed as being between 42%–57%
Observational studies have found a quarter of surgical patients have asymptomatic DVT at post-operative screening3
Patients undergoing major orthopaedic surgery represent a group that has a particularly high risk for VTE
Deep vein thrombosis (DVT) rates are based on the use of mandatory venography in prospective clinical trials published between 1980 and 2002, in which patients recieved either no prophylaxis or placebo.
Pulmonary embolism (PE) rates were derived from prospective studies that may have used thromboprophylaxis.
There are certain risk factors which make patients going into surgery more susceptible to developing VTE. Surgical patients and patients with trauma:5
1 in 20 people will have a VTE at some time in their life and approximately half of the cases are associated with prior hospitalisation for medical illness or surgery
VTE causes a larger number of deaths than the combined mortality due to:7
VTE is the most common preventable cause of in-hospital death8
The general risk factors associated with the development of venous thromboembolism (VTE):
Prescribing Information
Fragmin (dalteparin sodium) 10,000 IU/0.4ml solution for injection
Fragmin (dalteparin sodium) 10,000 IU/1 ml solution for injection
Fragmin (dalteparin sodium) 10,000 IU/4ml solution for injection
Fragmin (dalteparin sodium) 100,000 IU / 4ml Multidose Vial solution for injection
Fragmin (dalteparin sodium) 12,500 IU/0.5ml solution for injection
Fragmin (dalteparin sodium) 15,000 IU/0.6ml solution for injection
Fragmin (dalteparin sodium) 18,000 IU/0.72ml solution for injection
Fragmin (dalteparin sodium) 2500 IU solution for injection
Fragmin (dalteparin sodium) 5000 IU solution for injection
Fragmin (dalteparin sodium) 7,500 IU/0.3 ml solution for injection
Fragmin (dalteparin sodium) Graduated Syringe 10,000 IU/ml Solution for Injection
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