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Dosing           DosingIBRANCE® Dosing
 
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Clinical TrialsIBRANCE® Clinical TrialsIBRANCE® PALOMA-2 Trial
 
IBRANCE® PALOMA-3 Trial
Patient ProfilesThe Ibrance® PatientPatient ProfilesAllison - Postmenopausal with comorbiditiesBecky - Postmenopausal with bone-only diseaseELEVATE MasterclassSupport and ResourcesSupport and ResourcesIBRANCE Service SupportMaterials
 
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The content of this website has been produced in line with the IBRANCE® Summary of Product Characteristics. IBRANCE® (palbociclib) Prescribing Information for the UK click here.  Adverse event reporting information can be found at the bottom of the page.

Confidence Built on Evidence1-7

IBRANCE® (palbociclib) is indicated for the treatment of HR+ HER2- locally advanced or metastatic breast cancer in combination with an AI, or in combination with fulvestrant in women who have received prior endocrine therapy. In pre- or perimenopausal women, the endocrine therapy should be combined with a LHRH agonist.1

Dosing

Dosing and monitoring requirements for IBRANCE®

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Clinical Trials

IBRANCE® PALOMA-2 and PALOMA-3 Clinical Trial Results, including efficacy and safety outcomes

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Safety

Important safety information and safety outcomes from IBRANCE® PALOMA Clinical Trials

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Real World Evidence

Real-world evidence for IBRANCE® (palbociclib) in HR+ HER2- advanced Breast Cancer

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ELEVATE Masterclass

View on demand content from our promotional medical education programme

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Service Support
  • Non-Medical Prescribing (NMP) Service Implementation
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  • Models of Care - National Case Studies
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AI : Aromatase Inhibitor,  ET : Endocrine Therapy,  HR+/HER2– : Hormone Receptor Positive / Human Epidermal Growth Factor Receptor 2 Negative,  LHRH : Luteinizing Hormone-Releasing Hormone,  mBC : metastatic Breast Cancer

References

IBRANCE® Summary of Product Characteristics for the UK click here.Finn RS, et al. N Engl J Med 2016;375:1925–1936.Rugo HS, et al. Breast Cancer Res Treat 2019;174:719–729.Rugo HS, et al. NPJ Breast Cancer 2022;8:114.Slamon DJ, et al. J Clin Oncol. 2024;42(9):994-1000Rugo HS, et al. ESMO Open 2025;10(1):104103Cristofanilli M, et al. Lancet Oncol 2016;17:425–439.
PP-IBR-GBR-6745. November 2025

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