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Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

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For Inflectra® (infliximab) Prescribing Information for Great Britain click here.
For Inflectra® (infliximab) Prescribing Information for Northern Ireland click here
Adverse event reporting information can be found at the bottom of the page.

Safety profile and efficacy



Crohn's Disease safety guidance


In Adults

Inflectra is indicated for:

  • Treatment of moderately to severely active Crohn's disease, in adult patients who have not responded despite a full and adequate course of therapy with a corticosteroid and/or an immunosuppressant; or who are intolerant to or have medical contraindications for such therapies.1

  • Treatment of fistulising, active Crohn's disease, in adult patients who have not responded despite a full and adequate course of therapy with conventional treatment (including antibiotics, drainage and immunosuppressive therapy).1

In Paediatrics

Inflectra is indicated for treatment of severely active Crohn's disease in children and adolescents aged 6 to 17 years, who have not responded to conventional therapy including a corticosteroid, an immunomodulator and primary nutrition therapy; or who are intolerant to or have contraindications for such therapies. Infliximab has been studied only in combination with conventional immunosuppressive therapy.1

Post-marketing safety

Post-marketing data of 4,393 patients has illustrated that the safety profile appears consistent with clinical studies for CT-P13 and reference infliximab, supporting the favourable risk/benefit balance for CT-P13 treatment.2
​​​​​​​Please see the link for Inflectra® (infliximab) Prescribing Information at the top of the page, and refer to Section 4.8 for a summary of the safety profile.

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Evidence – Crohn’s disease

Learn about the clinical evidence supporting the use of Inflectra in patients with Crohn’s disease

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Crohn’s disease dosing

Learn about the dosing and administration of Inflectra in patients with Crohn’s disease

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  1. Inflectra Summary of Product Characteristics.
  2. Lee SJ, et al. BioDrugs 2020 :doi : 10.1007/s40259-020-00421-2.
PP-IFA-GBR-0508. September 2021

Quick Links

Read about the safety profile and contraindications with Inflectra in patients with ulcerative colitis.

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PP-PFE-GBR-2688. December 2020