This site is intended only for healthcare professionals resident in the United Kingdom

Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

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For Inflectra® (infliximab) Prescribing Information for Great Britain click here.
For Inflectra® (infliximab) Prescribing Information for Northern Ireland click here
Adverse event reporting information can be found at the bottom of the page.

Safety profile and efficacy Contraindications

Rheumatoid Arthritis safety guidance

​​​​​​In Adults


Inflectra, in combination with methotrexate, is indicated for the reductions of signs and symptoms as well as the improvement in physical function in adult patients with active disease when the response to disease-modifying antirheumatic drugs (DMARDs), including methotrexate, has been inadequate.  Adult patients with severe, active and progressive disease not previously treated with methotrexate or other DMARDs.

In these patient populations, a reduction in the rate of the progression of joint damage, as measured by X-ray, has been deomnstrated (see section 5.1).1

Post-marketing safety

Post marketing data of 4,393 patients has illustrated that the safety profile appears consistent with clinical studies for CT-P13 and reference infliximab, supporting the favourable risk / benefit balance for CT-P13 treatment.2

Please see the link for Inflectra® (infliximab) prescribing information at the top of the page, and refer to section 4.8 for a summary of the safety profile.

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Evidence – Rheumatoid arthritis

Learn about the clinical evidence supporting the use of Inflectra in patients with rheumatoid arthritis

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Rheumatoid arthritis dosing

Learn about the dosing and administration of Inflectra in patients with rheumatoid arthritis

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*CT-P13 is marketed under different brand names including Inflectra and REMSIMA®.
CD=Crohn's disease; UC=Ulcerative colitis; CRP=C-reactive protein.
References
  1. Inflectra Summary of Product Characteristics.
  2. Lee SJ, et al. BioDrugs 2020 :doi : 10.1007/s40259-020-00421-2.
PP-IFA-GBR-0518. September 2021

Quick Links

Read about the safety profile and contraindications with Inflectra in patients with Crohn's disease. 

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PP-PFE-GBR-2688. December 2020

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