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Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

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For Inflectra® (infliximab) Prescribing Information for Great Britain click here.
Adverse event reporting information can be found at the bottom of the page.

Safety profile and efficacy Contraindications

Ulcerative Colitis safety guidance

In Adults

Inflectra is indicated for treatment of moderately to severely active ulcerative colitis in adult patients who have had an inadequate response to conventional therapy including corticosteroids and 6-mercaptopurine (6-MP) or azathioprine (AZA), or who are intolerant to or have medical contraindications for such therapies.1 

In Paediatrics

Inflectra is indicated for treatment of severely active ulcerative colitis in children and adolescents aged 6 to 17 years, who have had an inadequate response to conventional therapy including corticosteroids and 6-MP or AZA, or who are intolerant to or have medical contraindications for such therapies.1

Post-marketing safety

Post-marketing data of 4,393 patients has illustrated that the safety profile appears consistent with clinical studies for CT-P13 and reference infliximab, supporting the favourable risk/benefit balance for CT-P13 treatment.2

​​​​​​​Please see the link for Inflectra® (infliximab) Prescribing Information at the top of the page, and refer to Section 4.8 for a summary of the safety profile.

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Evidence – inflammatory bowel disease

Learn about the clinical evidence supporting the use of Inflectra inpatients with ulcerative colitis and crohn’s disease

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Ulcerative colitis dosing

Learn about the dosing and administration of Inflectra in patients with Ulcerative colitis

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References
  1. Inflectra Summary of Product Characteristics.
  2. Lee SJ, et al. BioDrugs 2020 :doi : 10.1007/s40259-020-00421-2.
PP-IFA-GBR-0509. September 2021

Quick Links

Read about the safety profile and contraindications with Inflectra in patients with rheumatoid arthritis. 

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For UK Healthcare Professionals*

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PP-PFE-GBR-3863. November 2021

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