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Clinical trial information, including study design and efficacy results
Important safety information and safety outcomes from clinical trials
Dosing and monitoring requirements for LORVIQUA®
LORVIQUA® as monotherapy is indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) previously not treated with an ALK inhibitor or whose disease has progressed after prior treatment with an ALK inhibitor.1
A third-generation ALK TKI, LORVIQUA® is designed to address the unmet medical needs of CNS progression and ALK resistance mutations in patients with ALK+ advanced NSCLC and has demonstrated efficacy in both treatment-naïve patients and those whose disease had progressed on a previous ALK TKI.2-6
As a 2nd line therapy LORVIQUA® has a generally manageable safety profile, with a low permanent discontinuation rate (3.4%) due to treatment-related AEs* and a once-daily dosing schedule, taken with or without food.1,7
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PP-UNP-GBR-7812. January 2024