Click here for Great Britain and Northern Ireland Prescribing Information for MYLOTARG®▼ (gemtuzumab ozogamicin) and cytarabine.
Adverse event reporting information can be found at the bottom of the page.
A short video (3.03 duration) explaining
-MYLOTARG's mechanism of action
-Leading to the rationale of MYLOTARG's fractionated dosing schedule
-The resulting efficacy and safety data from the ALFA-0701 study
-Summary of the NICE recommendation
A quick video (03.26 duration) that covers all the key points related to the pivotal Phase III ALFA-0701 study
- Study Design
- Baseline characteristics
- Induction and Consolidation courses
- Primary endpoint: Event Free survival results by cytogenetic group
- Secondary endpoint: Relapse Free Survival results
- Adverse Events reported
This video (3.33 duration) aims to illustrate the concept of MRD by aggregating findings from different disease areas, studies and results. Its main focus is on Acute Lymphoblastic Leukaemia and data on Acute Myeloid Leukaemia is shown at time point 2.40.
This video covers:
-Definition of MRD
-Detection
-Principles
-Relevance: Complete remission
-Impact on Survival rates and patient outcomes
Download the pdf
AML, Acute Myeloid Leukaemia; MRD, measurable residual disease
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