About Somavert
Learn about the efficacy and safety of Somavert, its tumour impact and its effect on co-morbidity management through clinical and real world data
ACRODAT
The acromegaly disease activity tool designed to help monitor your patients
Support & Resources
Advice and support services to help you and your patients optimise your experience with Somavert about the efficacy and safety of Somavert through clinical and real world data
Funding and Reimbursement
Learn about funding and reimbursement England, Scotland, Wales and Northern Ireland
Webinars
Watch and listen to acromegaly experts talk about various topics in the disease area as well as recordings from our National Nurse Meeting and the Acromegaly co-morbidity series
Click here for Somavert® (pegvisomant) Prescribing Information. Adverse event reporting information can be found at the bottom of the page.
Somavert is used in the treatment of adult patients with acromegaly who have had an inadequate response to surgery and/or radiation therapy and in whom an appropriate medical treatment with somatostatin analogues did not normalise IGF-I concentrations or was not tolerated.
ACRODAT
Learn about the acromegaly-specific disease activity tool that you can use to help monitor and optimise support for your acromegaly patients at every stage of their journey.
ACRODAT is a validated, web-based software medical device
Available as part of the commercial package offer for Somavert
Developed in collaboration with a panel of global acromegaly experts
No installation is required: ACRODAT is accessible on the majority of platforms including desktops, laptops and tablets
A guide to using ACRODAT
Learn more about the development of ACRODAT, how to add and evaluate patients and more in the ACRODAT user guide
Request an ACRODAT demo
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ACRODAT can be used to track acromegaly disease activity status from one appointment to the next
Monitors and highlights changes in five disease-specific parameters
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ACRODAT enables an ongoing holistic overview of each patient’s acromegaly
Categorises patients based on stable, mild or significant levels of disease activity
** This is an optional area where footnotes can live.
How it works
A simple four step process to help track your patients' progress
Following registration, each authorised user in your clinic can add a new patient or access existing patient data which is stored in encrypted form within the searchable ACRODAT database
Step 1: Adding patients
Prior to each patient visit, you can generate a patient and visit-specific code. This enables the patient to log into a patient-specific side of the site and complete a quality of life (QoL) questionnaire for their upcoming visit. This can be done at home or in the waiting room beforehand. Alternatively, you can input QoL information in discussion with your patient during their consultation with you.
Step 2: Inviting a patient to complete AcroQoL questionnaire
At each patient visit, you will be asked to input brief information about clinical history and disease-specific parameters into the database.
Step 3: Data input
Using a validated algorithm created in collaboration with acromegaly experts, ACRODAT calculates each patient’s current overall disease activity status. Patient data input over a period of time can be viewed graphically or exported as an Excel file.
Step 4: Assessing results and exporting data
Example patient status graphs
Overall Status graph
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Symptoms graph
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IGF-I graph
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Quality of Life graph
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Why monitor?
Quality of life is commonly impaired in people with acromegaly, even after successful treatment1-3
Some patients are never asked about the psychological impact of their condition4
Acromegaly has a huge variety of symptoms and comorbidities, and hence there are equal number of key players involved in optimising care for patients with the condition1-5. However, the psychological aspect of dealing with acromegaly - together with the potential psychophysiological impact of pituitary hormone production imbalances caused by the condition itself - is something that can go overlooked 3-6.
How ACRODAT facilitates a holistic approach to acromegaly care
ACRODAT incorporates the AcroQOL questionnaire, a validated acromegaly-specific quality of life questionnaire7 .By capturing acromegaly-specific patient data on both the psychological and physical impact on quality of life for people living with the condition, ACRODAT provides a straightforward and systematic way for you to identify patients who may require further psychological support.
Explore more
Contact us
To find out more about ACRODAT, supporting patients or ordering more starter kits
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References:
1. Melmed S, et al. A Consensus Statement on acromegaly therapeutic outcomes. Nat Rev Endocrinol 2018;14:552-61
2. Geraedts VJ, et al. Predictors of Quality of Life in acromegaly: no consensus on biochemical parameters. Frontiers in Endocrinol 2017;8(40):1–14.
3. Crespo I, et al. Update on quality of life in patients with acromegaly. Pituitary 2017;20(1):185–8.
4. Wayne Brown. Alone in my universe: Struggling with an orphan disease in an unsympathetic world. Indiana, United States. iUniverse. May 2011: 268.
5. Chanson P and Salenave S. Acromegaly. Orphanet J Rare Dis 2008;3:1–17.
6. Gurel MH, et al. Patient perspectives on the impact of acromegaly: results from individual and group interviews. Patient Preference and Adherence 2014;8:53–62.
7. Webb SM, Prieto L, BadiaX, et al. Acromegaly Quality of Life Questionnaire (ACROQOL) a new health related quality of life questionnaire for patients with acromegaly: development and psychometric properties. Clin Endocrinol (Oxf) 2002;57:251–258.
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