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Adverse event reporting can be found at the bottom of the page
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Prescribing Information for TOMUDEX® (raltitrexed) and adverse event reporting information can be found at the bottom of the page.
TOMUDEX (raltitrexed) is indicated for use as a palliative treatment of advanced colorectal cancer where 5-fluorouracil (5-FU) and folinic acid based regimens are either not tolerated or inappropriate1.
This may include patients who have cardiotoxicity associated with fluoropyrimidine based treatments2. Click here to learn more about TOMUDEX as an option for these patients.
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Raltitrexed must only be given by or under the supervision of a physician who is experienced in cancer chemotherapy, and in the management of chemotherapy-related toxicity. Patients undergoing therapy should be subject to appropriate supervision so that signs of possible toxic effects or adverse reactions (particuarly diarrhoea) may be detected and treated promptly1.
References:
Prescribing Information
TOMUDEX:
TOMUDEX® (raltitrexed) 2 mg powder for solution for infusion – Prescribing Information Legal Category: POM. Basic NHS Price: 1 vial £148.75
OXALIPLATIN:
Oxaliplatin Vial 50mg/10ml Legal Category: POM. Basic NHS Price: 1 vial £156.75
Oxaliplatin Vial 100mg/20ml Legal Category: POM. Basic NHS Price: 1 vial £313.50
Oxaliplatin Vial 200mg/40ml Legal Category: POM. Basic NHS Price: 1 vial £627.00
Oxaliplatin 5mg/ml Concentrate for Solution for Infusion - Prescribing Information
FLUOROURACIL:
Fluorouracil Vial 500mg/20ml Legal Category: POM. Basic NHS Price: £64.00
Fluorouracil Vial 25mg/ml Legal Category: POM. Basic NHS Price: £32.00
Fluorouracil 25mg/ml Injection - Prescribing Information
Fluorouracil Vial 50mg/ml Legal Category: POM. Basic NHS Price: £64.00
Fluorouracil Vial 500mg/10ml Legal Category: POM. Basic NHS Price: £32.00
Fluorouracil Vial 2.5g/50ml Legal Category: POM. Basic NHS Price: £32.00
Fluorouracil 50mg/ml Injection - Prescribing Information
Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search
for MHRA Yellow Card in Google Play or Apple App Store
Adverse events should also be reported to Pfizer Medical Information on 01304 616161
To access further materials, resources and receive communication about medicines and vaccines promoted by Pfizer.
This site is intended only for healthcare professionals resident in the United Kingdom. If you are a member of the public wishing to access information on a specific medicine, please visit www.medicines.org.uk/emc
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These pages are not intended for patients or for members of the general public. The healthcare professional web pages contain promotional content.
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If you select 'No', you will be redirected to Pfizer.co.uk where you will be able to access reference information on Pfizer's prescription medicines.
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PP-PFE-GBR-3863. November 2021