Click here for Trumenba®▼ (meningococcal group B vaccine (recombinant, adsorbed)) Prescribing Information for Great Britain (GB) and Northern Ireland (NI). Adverse event reporting information can be found at the bottom of the page.
Trumenba (meningococcal group B vaccine (recombinant, adsorbed)) is indicated for active immunisation of individuals 10 years and older to prevent invasive meningococcal disease caused by Neisseria meningitidis serogroup B.1
Trumenba is a vaccine composed of 2 recombinant lipidated factor H binding protein (fHbp) variants.1 fHbp is found on the surface of meningococcal bacteria and helps bacteria to avoid host immune defences.
fHbp variants segregate into 2 immunologically distinct subfamilies, A and B.1 Over 91%** of MenB strains express sufficient levels of fHbp subfamily A or B to be susceptible to bactericidal killing by Trumenba induced antibodies.
**A survey of over 2,150 different invasive meningococcal serogroup B isolates collected from 2000-2014 in 7 European countries, the US and Canada demonstrated that over 91% of all meningococcal serogroup B isolates expressed sufficient levels of fHbp to be susceptible to bactericidal killing by vaccine-induced antibodies.1.
Trumenba offers two dosing schedules for adolescents and young adults1
This includes 2 doses (0.5ml each) administered 6 months apart.
This includes 2 doses (0.5ml each) administered at least 1 months apart, followed by a third dose at least 4 months after the second dose.
Trumenba can be co-administered concomitantly with1 :
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PP-PFE-GBR-3863. November 2021
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