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Click here for VELSIPITY▼ (etrasimod) Prescribing Information. Adverse event reporting can be found at the bottom of the page.

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VELSIPITY is indicated for the treatment of patients 16 years of age and older with moderately to severely active ulcerative colitis (UC) who have had an inadequate response, lost response, or were intolerant to either conventional therapy, or a biological agent.1

Induction responders (post hoc analysis)Efficacy among induction responders 

Clinical remission among induction responders at ELEVATE UC 52 (post-hoc analysis)2

Adapted from Vermeire S et al. 2023.2

Limitations: Results from this prespecified post hoc analysis should be evaluated with 
caution as head-to-head, randomised trials provide the most reliable comparative efficacy 
evidence. This post hoc analysis was conducted at Week 52 approximating to responder 
re-randomisation study design among patients who did or did not achieve clinical 
response at the end of the 12-week induction period in ELEVATE UC 52.2,3


ReferencesClinical remission is defined as a stool frequency subscore of 0 (or of 1 with a ≥1-point decrease from baseline), a RB subscore of 0, and an endoscopy score ≤1 (excluding friability).1Clinical response is defined as a ≥2-point and a ≥30% decrease in baseline in a modified Mayo score and a ≥1-point decrease from baseline in an RB subscore or an absolute RB subscore ≤1.1Syptomatic response

Read about symptomatic response with VELSIPITY in a post hoc analysis. 

SEE THE DATA HERELoading
CI - confidence interval; RB - rectal bleeding.References:1. VELSIPITY Summary of Product Characteristics. 
2. Vermeire S et al. Abstract P582 for the 18th Congress of European Crohn’s and Colitis Organisation 2023, Copenhagen, Denmark. 
3. Sandborn WJ et al. Lancet 2023;401(10383):1159-1171.
Efficacy
PP-V1A-GBR-0020. August 2024

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

for MHRA Yellow Card in Google Play or Apple App Store

 

Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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