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About VYNDAQEL

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Study DesignEfficacySafety ProfileDosingSupporting Resources Supporting ResourcesNICE Final Draft GuidanceAvailability in Scotland2021 ESC Heart Failure GuidelinesRisk Minimisation MaterialContact usMaterials

Click here for VYNDAQEL®▼ (tafamidis) Prescribing Information. 

About VYNDAQEL

VYNDAQEL stabilises TTR, the destabilisation of which causes ATTR amyloidosis1,2

Indication

VYNDAQEL 61 mg is indicated for the treatment of wild-type or hereditary transthyretin amyloidosis in adult patients with cardiomyopathy (ATTR-CM)1

Amyloid light chain (AL) amyloidosis must be excluded before starting treatment with VYNDAQEL

ATTR-CM is a rare condition that is life-threatening, under-recognised and under- or mis-diagnosed3,4

Learn about the efficacy of VYNDAQEL in patients with ATTR-CM

ATTR-ACT results Loading

The prognosis of patients with ATTR-CM worsens with continued amyloid deposits, therefore early diagnosis is key to improving patient outcomes3,6

VYNDAQEL stablises TTR, slowing dissociation to monomers1,7

See how VYNDAQEL works to treat ATTR-CM

ATTR-CM=transthyretin amyloid cardiomyopathy; TTR=transthyretin. 

Explore moreWe have a team ready to support you with any queries. 
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Navigate the Suspect & Detect Pfizer promotional website to learn more about ATTR-CM and its diagnosis

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References:

VYNDAQEL 61 mg (tafamidis) Summary of Product Characteristics.Castano A, Narotsky D, Maurer MS. Expert Analysis. American College of Cardiology. October 14, 2015. Available at:
https://www.acc.org/Latest-in-Cardiology/Articles/2015/10/13/08/35/Emerging-Therapies-for-Transthyretin-Cardiac-Amyloidosis [Last accessed February 2024].
Witteles EM, Bokhari S, Damy T, et al. JACC Heart Fail. 2019;7(8):709–716.Lane T, Fontana M, Martinez-Naharro A, et al. Circulation. 2019;140:16–26.Vieira M, Saraiva MJ. Biomol Concepts. 2014;5(1):45–54.Maurer MS, Elliott P, Comenzo R, Semigran M, Rapezzi C. Circulation. 2017;135(14):1357–1377.Bulawa CE, Connelly S, DeVit M, et al. Proc Natl Acad Sci U S A. 2012;109:9629–9634.
PP-VYN-GBR-1258. February 2024

Learn about the efficacy of VYNDAQEL in patients with ATTR-CM

ATTR-ACT results Loading

View VYNDAQEL dosing information

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Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

for MHRA Yellow Card in Google Play or Apple App Store

 

Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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