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About VYNDAQEL

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Study DesignEfficacySafety ProfileDosingSupporting Resources Supporting ResourcesNICE Final Draft GuidanceAvailability in Scotland2021 ESC Heart Failure GuidelinesRisk Minimisation MaterialContact usMaterials

Click here for VYNDAQEL®▼ (tafamidis) Prescribing Information. 

VYNDAQEL is accepted for use within NHS Scotland

Scottish Medicines Consortium (SMC) Advice:1

Advice: Following a second resubmission assessed under the end of life and orphan medicine process - 
VYNDAQEL (tafamidis) is accepted for use within NHS Scotland.

Indication under review: for the treatment of wild-type and hereditary transthyretin amyloidosis in adult patients with cardiomyopathy (ATTR-CM).

In a phase III study, 30 months of treatment with tafamidis (as meglumine) significantly reduced the risk of all-cause mortality and cardiovascular-related hospitalisation compared with placebo, in patients with wild-type or hereditary ATTR-CM.

This advice applies only in the context of an approved NHS Scotland Patient Access Scheme (PAS) arrangement delivering the cost-effectiveness results upon which the decision was based, or a PAS/ list price that is equivalent or lower.

This advice takes account of the views from a Patient and Clinician Engagement (PACE) meeting.
To view the advice in full, visit the SMC Website

If you are a healthcare professional based in Scotland and would like to learn more about how to access VYNDAQEL, get in touch with Pfizer here.

References:

Scottish Medicines Consortium (SMC). Vyndaqel November 2023. [SMC2585] Available at: https://www.scottishmedicines.org.uk/medicines-advice/tafamidis-vyndaqel-2nd-resubmission-smc2585/ Accessed March 2024. 
PP-VYN-GBR-1337 March 2024

Learn about the efficacy of VYNDAQEL in patients with ATTR-CM

ATTR-ACT studyLoading

Learn about the efficacy of VYNDAQEL in patients with ATTR-CM

ATTR-ACT studyLoading

A document containing information about VYNDAQEL to support formulary applications

Scotland Launch Notification Document 
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Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

for MHRA Yellow Card in Google Play or Apple App Store

 

Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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