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About VYNDAQEL

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Study DesignEfficacySafety & DosingModels of CareReal-world evidenceSupporting Resources Supporting ResourcesGuidelines and ReimbursementLong Term Extension StudyModels of CareConsensus Meeting ReportMaterialsVideosContact us

Click here for VYNDAQEL®▼ (tafamidis) Prescribing Information. 

The development of the consensus meeting report was organised and funded by Pfizer. It was reviewed by Pfizer for compliance
and accuracy purposes only.

​​Transforming the ATTR-CM journey: a UK roadmap to
improved diagnosis and referral
 



Background: ATTR-CM is a rare, progressive heart condition often underdiagnosed and misdiagnosed due to its non-specific symptoms and systemic barriers in the healthcare system1,2.

Objectives: Provide a roadmap to help guide cardiology and primary care teams in diagnosing, managing and referring ATTR-CM patients. Clarify accountability, applicable guidelines, and referral criteria to ensure timely and accurate diagnosis and optimal outcomes.

Methods: Between May and August 2025, committee members came together to produce a document containing actionable solutions to address the underlying issues in the diagnosis and treatment of ATTR-CM.

Outcomes: The roadmap identifies key challenges and provides recommendations to improve detection and treatment of patients with ATTR-CM.

Committee vision statement: Improved identification and earlier treatment of patients with ATTR-CM by 2028.

The consensus meeting report was co-authored by: Prof Marianna Fontana, Prof Lisa Anderson, Dr Sotiris Antoniou, Dr William Moody, Dr Chris Arden, Rebecca Hyland, Bal Bains, Vincent Graham Nesan Nicholas, Prof Gerald Carr-White, Dr Carol Whelan, Sheela Upadhyaya, Eric Low and Kaity Mcafferty.



Consensus meeting report: 'Transforming the ATTR-CM journey: a UK roadmap to improved diagnosis and referral'

The development of this consensus meeting report was organised and funded by Pfizer. This report is intended to be viewed online and is not for printing.

A consensus meeting report detailing the outputs and recommendations from an expert committee to improve diagnosis and referral for ATTR-CM patients in the UK, following a consensus-building workshop. Pfizer reviewed the document for accuracy and compliance purposes only, with outputs reflecting the consensus reached in the meeting and content developed by independent advisory firms who facilitated the workshop.

Click here for VYNDAQEL®▼ (tafamidis) Prescribing Information. 

DownloadLoading


ATTR-CM, Transthyretin amyloid cardiomyopathy; INT, Integrated neighbourhood team; CMR, Cardiovascular Magnetic Resonance; DPD, 3,3-diphosphono-1,2-propanodicarboxylic acid

1. American Heart Association. Transthyretin Amyloid Cardiomyopathy (ATTR-CM). Available at https://www.heart.org/en/health-topics/cardiomyopathy/what-iscardiomyopathy-in-adults/transthyretin-amyloid-cardiomyopathy-attr-cm (accessed December 2025).
2. Brito D, Albrecht FC, de Arenaza DP, et al. World Heart Federation Consensus on Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM). Glob Heart. 2023;18(1):59.
PP-VYN-GBR-2868. January 2026

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