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DosingDosingDosingSafetySafetySafetyClinical TrialsClinical TrialsXALKORI Clinical TrialsROS1+ NSCLC: PROFILE 1001ALK+ NSCLC: PROFILE 1014

Real World Evidence

Real World EvidenceReal World EvidenceSequential XALKORI® and Ceritinib in ALK+ NSCLCXALKORI® and Post-Progression Treatment in ALK+ NSCLC

The information on this website is based on data from adult patients with ALK+ NSCLC treated with XALKORI®(crizotinib), produced in line with the XALKORI®(crizotinib) Summary of Product Characteristics for Great Britain. For XALKORI® (crizotinib) Prescribing Information for Great Britain and Northern Ireland click here. Adverse event reporting information can be found at the bottom of the page.

XALKORI® (crizotinib):

An Established Inhibitor of ALK and ROS1

XALKORI® as monotherapy is indicated for:1

  • First-line treatment of adults with anaplastic lymphoma kinase (ALK)- positive advanced non-small cell lung cancer (NSCLC)
  • Treatment of adults with previously treated ALK-positive advanced NSCLC
  • Treatment of adults with ROS1-positive advanced NSCLC
  • Treatment of paediatric patients (age ≥ 6 to < 18 years) with relapsed or refractory systemic ALK-positive anaplastic large cell lymphoma (ALCL)
  • Treatment of paediatric patients (age ≥ 6 to < 18 years) with recurrent or refractory ALK-positive unresectable inflammatory myofibroblastic tumour (IMT)
The information on this website is based on data from adult patients with NSCLC only.
Dosing

Information on dosing, dose modifications and monitoring requirements for XALKORI®

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Clinical Trials

Clinical trial information, including study design and efficacy results

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Safety

Important safety information and safety outcomes from XALKORI® clinical trials

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ALCL: anaplastic large cell lymphoma, ALK: anaplastic lymphoma kinase, IMT: inflammatory myofibroblastic tumour, NSCLC: non-small cell lung cancer, ROS: reactive oxygen species

Reference

XALKORI® Summary of Product Characteristics for Great Britain click here. XALKORI® Summary of Product Characteristics for Northern Ireland click here.
PP-XLK-GBR-1342 | March 2024

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Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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