Information on how to access prescribing information and adverse event reporting can be found at the bottom of the page.
Dosing Guide
Preparation Guide
Shelf life and Storage
Aseptically inject each vial with 10 mL
sterile water for injections (not supplied) and use immediately1.
Withdraw the needle and shake the vial to give a clear solution.
Insert a gas relief needle through the vial closure after the product has dissolved to relieve the internal pressure (this is important to preserve product sterility)1.
Infusion bag: Further dilute the solution by transferring an appropriate volume to an infusion bag containing an infusion dilutent listed below1.
Infusion syringe: Further dilute the solution by transferring an appropriate volume, combined with sufficient volume of either sodium chloride 9 mg/mL (0.9%) or dextrose 50 mg/mL (5%) solution for injection, to an infusion syringe1.
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Steps 1 to 3 above should not exceed 30 minutes1
Please refer to the full dosing table in the SmPC for more information
Paediatric doses may be prepared in an appropriately sized infusion bag or infusion syringe. Care should be taken when calculating the volume of administration of the dose.
Please refer to the SmPC for steps to prepare for use in an infusion syringe in paediatric patients aged 3 to 12 months.
Suitable infusion diluents for infusion bags:
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Abbreviations
cIAI, complicated intra-abdominal infection; CrCl, creatinine clearance; cUTI, complicated urinary tract infection; ESRD, end stage renal disease; HAP, hospital-acquired pneumonia; LTO, limited treatment options; VAP, ventilator-associated pneumonia; ELF, epithelial lining fluid; AMR, Antimicrobial Resistance; MIC, minimum inhibitory concentration; EUCAST, European Committee on Antimicrobial Susceptibility Testing.
Prescribing information
Zavicefta® (ceftazidime and avibactam)
Great Britain
Zavicefta®(ceftazidime and avibactam) 2g/0.5 g Powder for Concentrate for Solution for Infusion
Northern Ireland
Zavicefta®(ceftazidime and avibactam) 2g/0.5 g Powder for Concentrate for Solution for Infusion
View safety profile
Patient Risk Factors
Pathogen Coverage
AMS Resources
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