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Adverse event reporting can be found at the bottom of the page
Preparation Guide
Shelf life and Storage
Aseptically inject each vial with 10 mL
sterile water for injections (not supplied) and use immediately1,5.
Withdraw the needle and shake the vial to give a clear solution.
Insert a gas relief needle through the vial closure after the product has dissolved to relieve the internal pressure (this is important to preserve product sterility)1,5.
Infusion bag: Further dilute the solution by transferring an appropriate volume to an infusion bag containing an infusion dilutent listed below1,5.
Infusion syringe: Further dilute the solution by transferring an appropriate volume, combined with sufficient volume of either sodium chloride 9 mg/mL (0.9%) or dextrose 50 mg/mL (5%) solution for injection, to an infusion syringe1,5.
Steps 1 to 3 above should not exceed 30 minutes1
Please refer to the full dosing table in the SmPC for more information
Paediatric doses may be prepared in an appropriately sized infusion bag or infusion syringe. Care should be taken when calculating the volume of administration of the dose.
Please refer to the SmPC for steps to prepare for use in an infusion syringe in paediatric patients aged 3 to 12 months.
Infusion diluents1,5
Suitable infusion diluents for infusion bags:
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Abbreviations
cIAI, complicated intra-abdominal infection; cUTI, complicated urinary tract infection; HAP, hospital-acquired pneumonia; VAP, ventilator-associated pneumonia; AMR, Antimicrobial Resistance.
Prescribing information
Click here for Prescribing Information for Zavicefta® (ceftazidime and avibactam)
References
Dry powder vial |
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After reconstitution |
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After dilution |
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Abbreviations
cIAI, complicated intra-abdominal infection; cUTI, complicated urinary tract infection; HAP, hospital-acquired pneumonia; VAP, ventilator-associated pneumonia; AMR, Antimicrobial Resistance.
Prescribing information
Click here for Prescribing Information for Zavicefta® (ceftazidime and avibactam)
References
These pages are not intended for patients or for members of the general public. The healthcare professional web pages contain promotional content.
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*The ABPI Code definition for healthcare professional is members of the medical, dental, pharmacy and nursing professionals and any other persons who in the course of their professional activities may administer, prescribe, purchase, recommend or supply a medicine.
PP-PFE-GBR-3863. November 2021