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Identifying a CAP patient who may benefit from Zinforo®

Listen to Professor Antoni Torres as he discusses the challenges involved in treating community-acquired pneumonia. 

In CAP patients, initial antimicrobial therapy failure is associated with up to 5 days longer in hospital and 3x higher mortality2,8,9

George, 70-year-old nursing home resident presented with fever, cough and sputum production*

Severity
​​​​​​​
  • PORT score IV (severe)​​​​​​​
    • 70-year-old male
    • RR >30/min
    • Temperature >40°C
    • Nursing home resident
History/comorbidities
​​​​​​​
  • History of smoking
Risk factors for difficult-to-treat infection
​​​​​​​
  • Age >65 years
  • Recurrent infection (hospitalised for pneumonia 3 months ago)
  • Previous antibiotic use

Marco presented with fever, cough and pleuritic chest pain and there has been no improvement with ceftriaxone*

Severity
​​​​​​​
  • PORT score IV (severe)
    • 78-year-old male
    • Chronic renal disease
    • Pulse >125 bpm
    • RR >30/min
    • No clinical improvement within 72 hours of ceftriaxone initiation
History/comorbidities
​​​​​​​
  • Renal insufficiency
  • Recent alcoholism
Risk factors for difficult-to-treat infection​​​​​​
​​​​​​​
  • Age >65 years
  • Medical comorbidities
  • Alcoholism

Marie presented with fever, dyspnoea and cough*

Severity
​​​​​​​
  • PORT score III (moderate)
    • 56-year-old female
    • PO2<90% (upon admission)
    • Blood glucose >250 mg/dL
    • Increasing oxygen requirements to maintain oxygen saturation
History/comorbidities
​​​​​​​
  • Mild asthma
  • Diabetes
Risk factors for difficult-to-treat infection
​​​​​​​
  • Recent antibiotic exposure for URTI within previous 3 months

When there’s no time to wait, clinical trial evidence supports the use of Zinforo in your CAP patients§3,4

Explore More

Read several cSSTI patient profiles describing potential scenarios where Zinforo could be a treatment of choice. 

Access cSSTI patient profiles

To learn more about the efficacy of Zinforo in a real-world setting, explore the CAPTURE study. 

View CAPTURE study data

*The examples described here are not actual patients, but fictitious representations of scenarios for which Zinforo could be considered.
§ Refer to SmPC for further information on Zinforo1
 
Abbreviations
​​​​​​​
CAP, community-acquired pneumonia; cSSTI, complicated skin and soft tissue infections; ICU, intensive care unit; RR, respiratory rate; URTI, upper respiratory tract infection; PORT, Pneumonia Patient Outcomes Research Team.
References
  1. ZINFORO. Summary of Product Characteristics
  2. Ott SR, et al. Eur Respir J 2012;39:611–18
  3. File TM, et al. Clin Infect Dis 2010;51:1395–405
  4. Eckburg P, et al. Infect Dis Clin Pract 2012;51:1395–405
  5. Laudano JB. J Antimicrob Chemother 2011;66(Suppl.3):iii11-iii18
  6. Garrison MW, et al. Expert Rev Anti Infect Ther 2012;10:1087-103
  7. Drusano, GL. J Antimicrob Chemother 2011;66(Suppl3):iii61–7
  8.  Ostermann H, et al. BMC Pulm Med 2014;14:36.
  9.  Menéndez R, et al. Thorax 2004;59:960–5.
PP-ZFO-GBR-0150. June 2021

Tolerability profile of Zinforo

Access date on the tolerability profile of Zinforo as established in key Phase III clinical trials.

View tolerability profile 

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