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Adverse event reporting can be found at the bottom of the page
CAPTURE was a retrospective cohort study relating to current treatment practice in the US. In CAPTURE, 'clinical success' was defined as clinical cure with no further need for antibiotic therapy or clinical improvement with switch to oral agents at end of Zinforo® treatment. As CAPTURE was a retrospective chart review study, it has the limitations inherent to this study design.5,10
†Zinforo is suitable for patients with a range of BMIs, and doesn't need to be dosed on a weight basis.4
‡Normal/mild renal insufficiency, or moderate or severe renal insufficiency. Overall clinical success rates were 88–91%.9
||CAPTURE was a retrospective cohort study relating to current treatment practice in the US. In CAPTURE, 'clinical success' was defined as clinical cure with no further need for antibiotic therapy or clinical improvement with switch to oral agents at end of Zinforo® treatment. As CAPTURE is a retrospective chart review study, it has the limitations inherent to this study design.5,10
*Shown not to be statistically significant10
Abbreviations
CAP, community-acquired pneumonia; cSSTI, complicated skin and soft tissue infections; CAPTURE, Clinical Assessment Program and TEFLARO Utilization Registry; NS, non significant
Prescribing Information
Zinforo® (ceftaroline fosamil)
Great Britain
Zinforo 600 mg powder for concentrate for solution for infusion
Northern Ireland
Zinforo 600 mg powder for concentrate for solution for infusion
References
Access data on the safety profile of Zinforo as established in key Phase III clinical trials
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PP-PFE-GBR-3863. November 2021