Stephen Armstrong explores how the NHS is putting its hopes—and maybe some money—into a handful of hospitals to work out how to go fully digital
AbstractObjective To examine the association of long term intake of gluten with the development of incident coronary heart disease.
Increasing pressure in NHS hospitals could be causing junior doctors to miss essential training, states the General Medical Council. In its most recent training survey featuring the views of more than 55,000 junior doctors, it found that junior doctors are regularly missing essential safety training, cautioning that it could lead to patient safety issues in the future.
Big data puts the link between alcohol consumption and risk of myocardial infarction under the microscope. This is a continuation of a long standing debate including the full study.
An understanding of how complex microbial communities can influence the pathogenesis of multiple diseases has implications for prevention, diagnosis, and treatment.This article offers you an insight into the current state of research and widen your view of the science of microbiomes.
Women who are overweight or obese in early pregnancy are more likely to have a child with cerebral palsy than women of normal weight, a large Swedish cohort study published in JAMA has shown.
Once one of the world’s deadliest diseases, smallpox’s complete eradication was the result of a worldwide deployment of a vaccine begun 50 years ago. To date it’s still the only human disease ever to disappear from Earth.
Patients with periodontitis have higher plasma concentrations of glycated haemoglobin (HbA1c) than people with healthy gums, and those with severe periodontitis have a significantly higher risk of developing diabetes, a Dutch study has found.
You may know that diabetes increases the risk of coronary artery disease, heart attack and stroke. But you may not know that research links diabetes to a higher risk of cardiomyopathy: thickening, stiffening and other changes in the heart muscle that limit the heart’s ability to pump blood throughout the body.
Over six years ago, in November 2010, the European Centre for Disease Prevention and Control (ECDC) published the first annual report of the European Antimicrobial Resistance Surveillance Network (EARS-Net). We are looking at the 2015 report and its findings, including a direct link.
Get access to the complete study to assess the overall effect of vitamin D supplementation on risk of acute respiratory tract infection, and to identify factors modifying this effect. Please sign in or register to read the full and comprehensive study. Already signed-in? Right this way...
Vitamin D supplementation is a hot topic, provoking passionate arguments for and against widespread supplementation. Recently in The BMJ we discussed the evidence, concluding that vitamin D supplements should not be taken by adults to prevent non-musculoskeletal disease. This is a continuation of the debate including the full study.
Detecting the occurrence of many diseases can be challenging without a blood test or other reliable screening tool. So researchers are now listening for the sounds of disease. Speech is a complex process that requires coordination with our brain, muscles, and respiratory system.
The next generation of diabetes treatments involve overriding glucose absorption in the kidneys, an uptick in gut hormones, and ditching the finger prick. Diabetes has become a global epidemic in the last quarter century, quadrupling to 422 million people living with the disease in 2014 from 108 million in 1980.
Jeans don’t always fit right, even though you’ve grabbed your size off the rack. The same can be said of medicinal dosages. They may seem right for your symptoms, height, weight, age and other health specifics. But tweaks are often still needed, especially with a progressive disease like Parkinson’s, where one day’s symptoms can differ from the next.
Lack of knowledge about placebos affects participants’ understanding of trials and breaches the ethical obligations of researchers, argue C R Blease, F L Bishop, and T J Kaptchuk. Informed consent requires researchers to provide participants with information about research that is accurate, complete, and understandable.
People with chronic insomnia are three times more likely to develop asthma than those without sleep problems, a study in the European Respiratory Journal suggests. Insomnia is known to be highly prevalent among asthmatic patients, as studies indicate a prevalence of 44-70%, compared with 7-37% in the general population.
Philanthropist Bill Gates is spearheading a coalition of partners to head off the next global epidemic by focusing on the development of vaccines for three emerging infectious diseases.
Failing to tackle the obesity “epidemic” could lead to an additional 670,000 cases of cancer and cost the NHS an additional £2.5bn by 2035, a recent report by Cancer Research UK claimed. Current guidance from the National Institute for Health and Care Excellence (NICE) describes the role primary care has in helping patients make a change to their lifestyles. But is it doing enough?
The more alcohol you drink, the greater your risk of developing some cancers. So why do people still drink more than the guidelines recommend? Are unclear and conflicting media messages partly to blame? An attempt to shed light on the issue...
Nearly 70 years since its establishment, the NHS is struggling to care for a vastly changed population. In the second article of his series, Gareth Iacobucci examines how societal trends have affected the health service.
More than 1000 doctors and other healthcare workers, including five former presidents of royal colleges, have written an open letter to the prime minister, Theresa May, and England’s health secretary, Jeremy Hunt, urging them to publish a new Tobacco Control Plan “without further delay” to address inequalities in health.
The idea that hospital staff might go around spreading infection arose in the 1780s and took about a hundred years to sink in. Whole genome bacterial sequencing can now track how many bacteria come to hospitals from outside and how many are spread by healthcare workers.
The objective is to determine the risk of venous thromboembolism associated with use of testosterone treatment in men, focusing particularly on the timing of the risk. Please sign in or register to read the full and comprehensive study. Already signed-in? Right this way...
Recent meta-analyses, commentaries, and bestselling books have called for an end to the proscription of saturated fats (SFAs), reversing years of dietary advice. Advocates of this shift draw support from prospective cohort studies since 1984, which when pooled find no association between SFA and risk of cardiovascular diseases.
Prediabetes is defined as an intermediate metabolic state between normoglycaemia and diabetes. This article offers a systematic review of the association between prediabetes and risk of cardiovascular disease caused mortality. Please sign in or register to read the full and comprehensive study. Already signed-in? Right this way...
Tim D Spector, professor of genetic epidemiology and Louis Levy, head of nutrition science discuss the up and downsides of taking additional vitamin D supplements during the winter months.
Ovarian cancer is one of the hardest diseases to diagnose. Its symptoms can also be confused for other less serious health conditions such as irritable bowel syndrome or PMT. But when ovarian cancer is found early at a localised stage, about 94% of patients live longer than five years after diagnosis.
With intensified competition, it is vital that pharmacy owners employ business strategies now to grow their customer base in the face of potential disruption to the industry. Here are five practical steps to protect your business and remain competitive that you can implement now.
United by a collaborative responsibility to manage the threat of antimicrobial resistance, Pfizer and 13 industry partners released a comprehensive plan of action that lays out four key commitments that we pledge to deliver by 2020 to reduce the rising incidence of antimicrobial resistance.
Patients present daily about symptoms that could represent a new diagnosis of cancer. This acticle is one of a series of occasional articles that highlight areas of practice where management lacks convincing supporting evidence.
Common viruses are now being engineered to seek out and destroy cancer cells.
Computer programmers and data scientists are working with microbiologists and chemists to unlock the medicinal potential of natural products.
Vaccines have a long and storied history, from milkmaids’ cowpox pustules to snorting the scabs of infected people. Read some of the most memorable moments.
Who would not want to know the medicines they are taking are authentic? Nobody fancies brick dust, floor wax or anti-freeze in their medicine.
There has been a lack of national guidance and care pathways for primary care on when to offer testing for NAFLD. Investigation and referral of suspected NAFLD vary widely.
Mounting evidence that Zika virus infection in early gestation causes brain damage shows that Zika associated arthrogryposis may be neurogenic. In agreement, the mechanisms underlying the CZS phenotype would be a tropism of the virus to neuronal cells, or vascular disorders, as in the fetal brain disruption sequence.
The biggest survey of mental health disorder and treatment in England has found that Women are more likely to have mental health problems than men, with young women at particularly high risk.
From discovering penicillin to mapping the genome, pharmaceutical innovation has changed our lives. Watch the journey from Molecule to Medicine.