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Dosing and administration
1 HOUR ADMINISTRATION REGIMEN
BESPONSA® is administered as an IV infusion over 1 hour in 21 or 28-day cycles (on days 1, 8 and 15)1
- Due to the risk of VOD for patients proceeding to HSCT, the recommended duration of treatment is 2 cycles. A third cycle may be considered for those patients who do not achieve CR/CRi and MRD negativity after 2 cycles1
- Patients who do not achieve CR/CRi within 3 cycles should discontinue treatment1
- For patients not proceeding to HSCT, a maximum of 6 cycles may be administered1
*Cycle 1 is 3 weeks in duration, but may be extended to 4 weeks if the patient achieves a CR/CRi, and/or to allow recovery from toxicity.1
CR, complete remission; CRi, complete remission with incomplete haematological recovery of peripheral blood counts; HSCT, haematopoietic stem cell transplant; IV, intravenous; MRD, minimal residual disease.
PP-INO-GBR-0132. May 2020
Additional administration information
*10,000/mm3
ALL, acute lymphoblastic leukaemia; PBC, peripheral blast count
PP-INO-GBR-0132. May 2020
Prescribing information
BESPONSA® (inotuzumab ozogamicin) 1 mg powder for concentrate for solution for infusion
Legal category: Prescription only medicine. Cost: £8,048 per vial.
Click here to access the BESPONSA Summary of Product Characteristics hosted on Datapharm’s ‘electronic Medicines Compendium’.
▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 of the SmPC for how to report adverse reactions.
Cytarabine 20 mg/mL and 100 mg/mL solution for infusion or injection
Legal category: Prescription only medicine. Basic NHS price: Cytarabine 100 mg/mL, supplied as single vials containing 100 mg/mL cytarabine in 10 mL (1 g), £39.00 or 20 mL (2 g), £77.50. Cytarabine 20 mg/mL supplied as vials containing 20 mg/mL cytarabine in 5 mL (100 mg) in packs of 5, £20.48 or 25 mL (500 mg) as single vials, £19.50.
Click here to access the cytarabine 20 mg/mL and click here to access the cytarabine 100 mg/mL Summary of Product Characteristics hosted on Datapharm’s ‘electronic Medicines Compendium’.
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