Champix tolerability

The tolerability of CHAMPIX has been carefully assessed.1

What patients can expect when quitting – with or without treatment:

  • Quitting smoking may result in nicotine withdrawal syndrome, which produces a range of effects, including depressed mood2,3
  • These effects may last from a few days to more than 10 weeks2

Support your patients through nicotine withdrawal with CHAMPIX
CHAMPIX has been shown to reduce cravings and withdrawal symptoms1

The most common adverse events with CHAMPIX1
Nausea 32%
Insomnia 19.1%
Headache 17.7%
Abnormal dreams 13.8%
Nasopharyngitis 10.7%


  • Nausea is mostly mild to moderate, occurs early in treatment and infrequently results in discontinuation1
  • CHAMPIX has low discontinuation rates due to adverse events, comparable to placebo (11.4% vs. 9.7%)1
  • Based on clinical trial experience to date, CHAMPIX has no clinically meaningful drug interactions1

Please refer to the Summary of Product Characteristics for further information about adverse events that have been reported during/after Champix therapy

1. CHAMPIX Summary of Product Characteristics
2. McEwen A et al. Manual of smoking cessation. A guide for counsellors and practitioners. 2006, Addiction Press: Blackwell Publishing.
3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Text Revision. Washington, DC: American Psychiatric Association; 2000.
4. West R, Shiffman S. Fast Facts. Smoking cessation. Indispensable guides to clinical practice. 2004, Oxford: Health Press.

PP-CHM-GBR-3272.  May 2020