Anidulafungin (Ecalta®)

Anidulafungin (Ecalta®) – not just another echinocandin

  • No dose adjustment required in hepatic or renal impairment1
  • No known drug interactions1,2
  • A favourable pharmacokinetic profile compared to other echinocandins3
  • Better efficacy and significantly higher global success rate versus the gold standard fluconazole in the treatment of candidaemia4
  • Ecalta® patent expiry is in March 2018. Following patent expiry, cost savings may be available5

Ecalta - Not Just Another Echinocandin

References
1. Ecalta® Summary of Product Characteristics.
2. Vazquez JA. Clin Ther 2005;27(6):657–673.
3. Kim R, et al. Expert Opin Pharmacother 2007;8(10):1479–1492.
4. Reboli AC, et al. N Engl J Med 2007;356:2472–2482.
5. Pfizer data on file, 2016.

 

 

 

Date of Preparation: January 2018

PP-ERA-GBR-0199

Prescribing Information

Ecalta® (Anidulafungin) – SPC
Legal Category: POM      Basic NHS cost: 100 mg 1 vial per pack £299.99

Diflucan® (fluconazole) 10 mg/ml powder for oral suspension – SPC  
Legal Category: POM      Basic NHS Cost: Diflucan powder for oral suspension 10 mg/ml £16.61 

Diflucan® (fluconazole) 150 mg Capsules – SPC  
Legal Category: POM      Basic NHS cost: Diflucan hard capsules 150 mg £7.12

Diflucan® (fluconazole) 2 mg/ml solution for infusion – SPC  
Legal Category: POM      Basic NHS cost: Diflucan 2 mg/ml solution for infusion 100 ml £29.28

Diflucan® (fluconazole) 200 mg hard capsules – SPC  
Legal Category: POM      Basic NHS cost: Diflucan hard capsules 200 mg £66.42

Diflucan® (fluconazole) 40 mg/ml powder for oral suspension – SPC  
Legal Category: POM      Basic NHS cost: Diflucan powder for oral suspension 40 mg/ml £66.42

Diflucan® (fluconazole) 50 mg hard capsules – SPC  
Legal Category: POM      Basic NHS cost: Diflucan hard capsules 50 mg £16.61   

Vfend® (voriconazole) – SPC 
Legal Category: POM      Basic NHS Cost: Pack of 28 50 mg tablets £275.68, Pack of 28 200 mg tablets £1,102.74, 30 ml vial of 200 mg powder for intravenous infusion £77.14, 30 ml vial of 200 mg powder for intravenous infusion with 50 ml bag containing Vfend solvent for solution for infusion £77.14, 100 ml bottle of 40 mg/ml powder for oral suspension £551.37