Voriconazole (Vfend®)

Voriconazole (Vfend®): for efficacy, patient outcomes1–3 and potential medium-term budgetary implications

  • Use of voriconazole, the gold-standard, recommended first-line treatment for invasive aspergillosis (IA), is supported by clinical trials and real-world evidence1, 4–6
  • Oral and IV voriconazole options deliver flexible treatment and prophylaxis for both adults and children2

 

IV, intravenous

References
1. Herbrecht R, et alN Engl J Med. 2002; 347(6): 408–15.
2. Vfend® Summary of Product Characteristics
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3. Marks DI, et alBr J Haematol. 2011; 155(3): 318–27.
4. Walsh TJ, et alClin Infect Dis. 2008; 46(30): 327–60.
5. Herbrecht R, et al. 2013-Update of the ECIL Guidelines for Antifungal Therapy in Leukemia and HSCT Patients (ECIL-5). Date accessed: June 2017.
6. Baddley JW, et alClin Infect Dis. 2010; 50(12): 1559–7.

 

 

 

Date of Preparation: June 2017

PP-VFE-GBR-0050

Prescribing Information

Vfend® (voriconazole) – SPC 
Legal Category: POM      Basic NHS Cost: Pack of 28 50 mg tablets £275.68, Pack of 28 200 mg tablets £1,102.74, 30 ml vial of 200 mg powder for intravenous infusion £77.14, 30 ml vial of 200 mg powder for intravenous infusion with 50 ml bag containing Vfend solvent for solution for infusion £77.14, 100 ml bottle of 40 mg/ml powder for oral suspension £551.37

Diflucan® (fluconazole) 10 mg/ml powder for oral suspension – SPC  
Legal Category: POM      Basic NHS Cost: Diflucan powder for oral suspension 10 mg/ml £16.61 

Diflucan® (fluconazole) 150 mg Capsules – SPC  
Legal Category: POM      Basic NHS cost: Diflucan hard capsules 150 mg £7.12

Diflucan® (fluconazole) 2 mg/ml solution for infusion – SPC  
Legal Category: POM      Basic NHS cost: Diflucan 2 mg/ml solution for infusion 100 ml £29.28

Diflucan® (fluconazole) 200 mg hard capsules – SPC  
Legal Category: POM      Basic NHS cost: Diflucan hard capsules 200 mg £66.42

Diflucan® (fluconazole) 40 mg/ml powder for oral suspension – SPC  
Legal Category: POM      Basic NHS cost: Diflucan powder for oral suspension 40 mg/ml £66.42

Diflucan® (fluconazole) 50 mg hard capsules – SPC  
Legal Category: POM      Basic NHS cost: Diflucan hard capsules 50 mg £16.61