On Demand

Dr Neggers: microbioma and metabolic consequences

Dr Neggers

Dr. Sebastian Neggers talks about the metabolic consequences of microbioma. In particular, this lecture was about children and starvation and how that affects microbioma.

On Demand

Dr van Leeuwaarde: hypogonadism in aging men

Dr van Leeuwaarde

Dr. Rachel van Leeuwaarde discusses a study looking at the efficacy of testosterone treatment for hypogonadism in elderly men, and how this will help manage patient expectations in practise.

On Demand

Dr Timmers: advances in primary adrenal insufficiency

Dr Timmers

Dr. Henri Timmers from RadboudUMC in The Netherlands talks about new monogenetic forms of adrenal insufficiency, and the importance of considering genetic mutations that could have occurred in certain rare cases.

On Demand

Professor Wass: kisspeptin signalling

Professor Wass

Professor John Wass from Oxford University discusses an abstract by Jenny Clarkson from Otago, New Zealand. The study looked at the relative importance of the paraventricular stimulus of kisspeptin onto GNRH neurones and the arcuate nucleate stimulus.

On Demand

Associate Professor Ragnarsson: common genetic variants in Cushing’s syndrome

Associate Professor Ragnarsson

Associate Professor Oskar Ragnarsson from Sahlgrenska University Hospital, Gothenburg, talks about a study he is involved with concerning the association between normalisation of urine free cortisol and certain polymorphisms in genes coding for the enzymes in the adrenal glands. He reflects on what this could mean for treatment for patients such as those with Cushing's syndrome.

On Demand

Dr Olsson: the incidence of malignancies in patients with non-functioning pituitary adenomas

Dr Olsson

Dr. Olsson from Sahlgrenska University Hospital, Gothenburg on the incidence of malignancies in patients with non-functioning pituitary adenomas.

On Demand

Dr Neggers: the important drivers of 'sweet tooth'

Dr Neggers

Dr. Sebastian Neggers from Erasmus Medical Centre Rotterdam, The Netherlands, discusses the important drivers of 'sweet tooth' and how glucose metabolism can be regulated.

On Demand

Dr van Leeuwaarde: early screening for breast cancer in women with MEN1

Dr van Leeuwaarde

Dr Rachel van Leeuwaarde from University Medical Centre Utrecht in the Netherlands, tells us about her recent findings on whether early screening for breast cancer should be started in women with multiple endocrine neoplasia 1 (MEN1).

On Demand

TKI to TKI sequencing in mRCC: a case study

Dr Emilio Porfiri

For prescribing information and adverse event reporting please see the link in the information panel on the RHS of this page.

This case study demonstrates how axitinib in 2nd line mRCC can be used as part of a successful treatment sequence, followed by immunotherapy in the third line setting. It also highlights that treatment with axitinib following cardiac failure may be safely resumed on an individual patient basis  and provide long-term benefit following dose reduction.

On Demand

Efficacy and safety of axitinib following quick progression in 1st line: a case study

Dr Jason Lester

For prescribing information and adverse event reporting please see the link in the information panel on the RHS of this page.

This case study addresses how axitinib can be used as part of a successful treatment regime in patients with hypertension and following an acute medical event. This case study also demonstrates how to achieve an extended duration of treatment with axitinib irrespective of duration of first line therapy.