This site is intended only for healthcare professionals resident in the United Kingdom

Information relating to specific disease areas aligned to Pfizer’s portfolio and other resources designed for Pfizer medicines.

See all Therapy areas

Click here for Somavert® (pegvisomant) Prescribing Information. Adverse event reporting information can be found at the bottom of the page.

Typical characteristics of acromegaly1,2

Local tumor effects

Visual impairment, headaches, pituitary infarction/destruction, optic/cranial nerve impingement

General

Soft-tissue swelling, fatigue, enlarged organs

Cutaneous and soft tissue

Enlarged hands, ‘spade-like’ fingers, feet, nose, coarsening of facial features, thick oily skin, increased sweating and skin odour, sweaty handshake, skin tags, increased heel pad thickness, thick lips and skin folds

Endocrine/metabolic

Carbohydrate intolerance, diabetes mellitus, hyperlipidaemia, goitre, hyperprolactinaemia, galactorrhoea

Cardiovascular

Congestive heart failure, hypertension, cardiomyopathy, left ventricular hypertrophy

Respiratory

Sleep apnoea, tongue enlargement, voice change

Gastrointestinal

Colonic polyps, diverticulosis

Neurological

Paraesthesia, somnolence, carpal tunnel syndrome

Musculoskeletal

Malocclusion, widely spaced teeth, prognathism, frontal bossing, enlarged sinuses and larynx, weakness, joint pains (shoulders, back, knees), osteoarthritis, degenerative arthritis of the spine, hips and knees

Psychosexual

Decreased libido, impotence, menstrual disturbance, depression, mania

Explore more

Contact us

To find out more about ACRODAT, supporting your patients or to order starter kits 

Contact us

Have your heard about ACRODAT?

An acromegaly specific Disease Activity Tool that can help monitor patients at every stage of their journey

Learn more


References:
  1. Aron DC, Findling JW, Tyrrell JB. Hypothalamus and pituitary. In: Greenspan FS, Gardner DG., editors. Basic and clinical endocrinology. 6th ed. Lange Medical Books/ McGraw-Hill Medical Publishing Division; 2001. p. 100-162.
  2. Melmed S, Kleinberg D. Anterior pituitary. In: Larsen PR, Kronenberg HM, Melmed S et al., editors. Williams textbook of endocrinology. 10th ed. Philadelphia, Pennsylvania: Saunders (Elsevier); 2003. p. 180-238.
PP-SOM-GBR-0950. June 2021

Acromegaly co-morbidities webinars

Watch and listen to our Rare Disease Insight series where expert speakers take a deep dive into the co-morbidities associated with acromegaly

Watch the webinars now

** This is an optional area where footnotes can live.

Colonic screening in acromegaly

Professor Aled Rees, Consultant in Endocrinology, University Hospital of Wales, Cardiff, explains how active acromegaly can increase the risk of colon cancer and shares a colon surveillance algorithm

Watch more expert webinars

For UK Healthcare Professionals*

These pages are not intended for patients or for members of the general public. The healthcare professional web pages contain promotional content.

I confirm that I am a healthcare professional* resident in the United Kingdom.

If you select 'No', you will be redirected to Pfizer.co.uk where you will be able to access reference information on Pfizer's prescription medicines.

*The ABPI Code definition for healthcare professional is members of the medical, dental, pharmacy and nursing professionals and any other persons who in the course of their professional activities may administer, prescribe, purchase, recommend or supply a medicine.

PP-PFE-GBR-2688. December 2020

Yes

No