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What is acromegalyHow is it diagnosedCharacteristicsSupport & ResourcesVideosMaterials

Click here for Somavert® (pegvisomant) Prescribing Information. 

DiagnosisPresentation

Most patients have unrecognised signs and symptoms for many years and may be diagnosed through a dental examination or testing done for other reasons.1,2 Although their outward appearance may have altered, it is often the symptoms of complications that lead patients to seek medical care.1

Diagnostic blood tests

The diagnosis can be confirmed with an Oral Glucose Tolerance Test (OGTT) or measurement of serum IGF-I levels (age and sex-adjusted). Although both growth hormone (GH) and IGF-I levels have been implicated as indicators of mortality, IGF-I is considered to be indicative of persistent clinical disease activity.3

Imaging

Imaging techniques such as computed tomography (CT) or magnetic resonance imaging (MRI) are used to determine the cause of GH overproduction (usually a pituitary adenoma) and provide further confirmation of the acromegaly diagnosis.2,4,5

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To find out more about homecare, supporting patients or ordering more starter kits

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Treating acromegaly​​​​​​​

Help find your Somavert patient's personal optimum by titrating doses 

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References:

Freda PU. Acromegaly diagnostic pitfalls. The Endocrinologist. 2004; 14(5):277-287.Melmed S, et al. A Consensus Statement on acromegaly therapeutic outcomes. Nat Rev Endocrinol 2018;26:1.Alexopoulou O, Bex M, Abs R et al. Divergence between growth hormone and insulin-like growth factor-I concentrations in the follow-up of acromegaly. J Clin Endocrinol Metab. 2008; 93(4):1324-1330.Ilie I, et al. Diagnosis of Acromegaly. Encyclopedia of Endocrine Diseases, Second Edition Vol 2 (Elsevier). 2018 p223-229Chanson, P and Salenave, S. Acromegaly. Orphanet journal of rare diseases. 2008. vol. 3 17. 
PP-SOM-GBR-1239. July 2023
Somavert efficacy

Discover IGF-I normalisation rates with Somavert

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