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Adverse event reporting can be found at the bottom of the page

About ATTR-CMATTR-CM Disease and Prevalence

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Suspect ATTR-CMClinical Red FlagsECHOCMRDiagnose ATTR-CMDPDRuling out ALGenetic TestingPatient ProfilesTreatment optionsSupporting ResourcesVirtual Centre Of ExcellenceMaterialsVideos

Click here for Vyndaqel®▼ (tafamidis) Prescribing Information.

ATTR-CM: A LIFE-THREATENING DISEASE THAT CAN GO UNDETECTED1



ATTR-CM is an underdiagnosed, progressive disease that can often be overlooked as a cause of heart failure.1

 

Early diagnosis and treatment of ATTR-CM are critical to extend life. 1-5

Early detection of red flags that build suspicion of ATTR-CM can facilitate timely referral and early diagnosis of ATTR-CM.5-8

The Virtual Centre of Excellence (VCoE) is an interactive digital hub designed to reduce knowledge gaps in the accurate diagnosis and treatment of ATTR-CM.

 Virtual Centre of Excellence (VCoE)Loading

The Virtual Centre of Excellence (VCoE) is an interactive digital hub designed to reduce knowledge gaps in the accurate diagnosis and treatment of ATTR-CM.

 Virtual Centre of Excellence (VCoE)Loading


Supporting
Resources
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Learn about one of the treatment options for ATTR-CM
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ATTR-CM= transthyretin amyloid cardiomyopathy.

References:

Witteles RM, et al. JACC Heart Fail. 2019;7(8):709–716.Maurer MS, et al. Circulation. 2017;135:1357–1377.Elliott P, et al. Circ Heart Fail. 2022;15:e008193.Maurer MS, et al. N Engl J Med. 2018;379(11):1007–1016.Garcia-Pavia P, et al. J Card Fail. 2025;31:525–533.Garcia-Pavia P, et al. Eur Heart J. 2021;23(4):512–526.Sperry BW, et al. Heart Failure Rev. 2022;27:1559–1565.Ioannou A, et al Circulation. 2022;146:1657–1670.Castaño A, et al. Heart Fail Rev. 2015;20(2):163–178.
PP-VYN-GBR-3242. August 2026

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