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Adverse event reporting can be found at the bottom of the page

About ATTR-CMAbout

Learn about ATTR-CM and uncover the differences between hereditary and wild-type ATTR-CM

Types of ATTR-CM

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Click here for Vyndaqel®▼ (tafamidis) Prescribing Information.

Current treatment options

Current standard of care treatment options available for ATTR-CM are aimed at symptom management, supportive care including pain management, nutritional and mobility support and mitigation of the effects of the disease on other organs.1

In February 2020, marketing authorisation in the United Kingdom was granted for Vyndaqel▼ (tafamidis), a transthyretin stabiliser, available as a once-daily 61 mg oral capsule, for the treatment of wild-type or hereditary transthyretin amyloidosis in adult patients with cardiomyopathy (ATTR-CM).2,3 
 

As of 19th June 2024,  Vyndaqel (tafamidis) is recommended by NICE as an option for treating wild-type or hereditary transthyretin amyloidosis with cardiomyopathy (ATTR-CM) in adults.4

Tafamidis is only recommended if the company provides it according to the commercial arrangement.

To learn about what this means for your eligible patients, follow the link below.

NICE Recommendation Loading

Please note that this links to a Pfizer promotional website intended for UK healthcare professionals only.

ATTR-CM=transthyretin amyloid cardiomyopathy,NICE= National Institute for Health and Care Excellence

References:Hawkins PN, Ando Y, Dispenzen A et al. Evolving landscape in the management of transthyretin amyloidosis. Ann Med. 2015; 47: 625–638;Vyndaqel 61 mg (tafamidis) Summary of Product Characteristics for GB available at: https://www.medicines.org.uk/emc/product/11141/smpc [Last accessed: June 2024];Vyndaqel 61 mg (tafamidis) Summary of Product Characteristics for NI available at: https://www.emcmedicines.com/en-gb/northernireland/medicine?id=37877680-6fdf-4ecc-9fb5-153830ad38b8
&type=smpc
[Last accessed: June 2024].
NICE. [TA984]. Tafamidis for treating transthyretin amyloidosis with cardiomyopathy. Available at: Overview | Tafamidis for treating transthyretin amyloidosis with cardiomyopathy | Guidance | NICE  (Accessed June 2024)
Learn more about VyndaqelVYNDAQEL® 61 mg (tafamidis) is indicated for the treatment of wild-type or hereditary transthyretin amyloidosis in adult pateints with cardiomyopathy (ATTR-CM).2,3
Amyloid light chain (AL) amyloidosis must be excluded before starting treatment with VYNDAQEL.2,3
Explore VyndaqelLoading
PP-VYN-GBR-1426. June 2024

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search 

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Adverse events should also be reported to Pfizer Medical Information on 01304 616161

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