ReFacto AF (moroctocog alfa) Prescribing Information for Great Britain click here. ReFacto AF (moroctocog alfa) Prescribing Information for Northern Ireland click here.
BeneFIX (nonacog alfa) Prescribing Information for Great Britain click here. BeneFIX (nonacog alfa) Prescribing Information for Northern Ireland click here.
Adverse event reporting information can be found at the bottom of the page.
Haemophilia is a lifelong condition requiring constant and careful management. The most common forms of haemophillia are caused by deficiency in a particular coagulation factor – factor VIII (FVIII) in haemophilia A and factor IX (FIX) in haemophilia B.
Haemophilia is quite rare; about 1 in 10,000 people are born with it1
Affects 1 in every 5,000 males.2
They do not have enough clotting factor VIII.
Affects 1 in every 25,000 males.2
They do not have enough clotting factor IX.
The chances of a child inheriting the haemophilia mutation depend on which of their parents has the mutated gene.1-3
About one-third of cases are known as sporadic haemophilia, which arises even though there is no family history of it. In these instances, it’s likely the mutation developed spontaneously when the baby was conceived.1
Bleeding into a joint or muscle causes:
Their blood does not have enough clotting factor therefore bleeding may stop and then start again, which prevents wounds from healing properly.
People with hemophilia can bleed inside or outside the body. Repeated bleeding in the same joint can cause severe pain, stiffness and weakness, leading to haemophilic arthropathy.
People with haemophilia are usually advised to seek medical help if1:
For your patients with haemophilia B
For your patients with haemophilia A
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PP-PFE-GBR-2688. December 2020