Information on how to access prescribing information and adverse event reporting can be found at the bottom of the page.
To optimize outcomes for patients who begin dopamine agonist therapy, routine follow-up of prolactin is imperative for guiding dose adjustment.1
Serum prolactin should be measured 1 month after initiating dopamine agonist therapy and routinely repeated, as necessary.1,2
Aside from monitoring prolactin levels and adjusting dopamine agonist therapy to achieve prolactin normalisation, other follow-up assessments should be conducted during treatment.1
Dopamine agonists should be given continuously for at least 2 years. After this time, therapy can be tapered and perhaps even discontinued if prolactin levels have remained at normal levels for 2 years and there is no visible tumor remaining on MRI.1
If treatment tapering/discontinuation is pursued, careful follow-up is required to monitor for recurrence.1
Dostinex (cabergoline) prescribing information can be found here
References
1.Melmed S, Casanueva FF, Hoffman AR, et al; Endocrine Society. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(2):273-288.
2.Halperin Rabinovich I, Cámara Gómez R, García Mouriz M, Ollero García-Agulló D; Grupo de Trabajo de Neuroendocrinología de la SEEN. Clinical guidelines for diagnosis and treatment of prolactinoma and hyperprolactinemia. Endocrinol Nutr. 2013;60(6):308-319.
See general information including pathophysiology and etiology
Understand what signs to look for and explore two patient case studies
Recognise which tests to order and what the results indicate
Determine therapy based on clinical and patient factors
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