Information on how to access prescribing information and adverse event reporting can be found at the bottom of the page.
To optimize outcomes for patients who begin dopamine agonist therapy, routine follow-up of prolactin is imperative for guiding dose adjustment.1
Serum prolactin should be measured 1 month after initiating dopamine agonist therapy and routinely repeated, as necessary.1,2
Aside from monitoring prolactin levels and adjusting dopamine agonist therapy to achieve prolactin normalisation, other follow-up assessments should be conducted during treatment.1
Dopamine agonists should be given continuously for at least 2 years. After this time, therapy can be tapered and perhaps even discontinued if prolactin levels have remained at normal levels for 2 years and there is no visible tumor remaining on MRI.1
If treatment tapering/discontinuation is pursued, careful follow-up is required to monitor for recurrence.1
Dostinex (cabergoline) prescribing information can be found here
1.Melmed S, Casanueva FF, Hoffman AR, et al; Endocrine Society. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(2):273-288.
2.Halperin Rabinovich I, Cámara Gómez R, García Mouriz M, Ollero García-Agulló D; Grupo de Trabajo de Neuroendocrinología de la SEEN. Clinical guidelines for diagnosis and treatment of prolactinoma and hyperprolactinemia. Endocrinol Nutr. 2013;60(6):308-319.
See general information including pathophysiology and etiology
Understand what signs to look for and explore two patient case studies
Recognise which tests to order and what the results indicate
Determine therapy based on clinical and patient factors
These pages are not intended for patients or for members of the general public. The healthcare professional web pages contain promotional content.
I confirm that I am a healthcare professional* resident in the United Kingdom.
If you select 'No', you will be redirected to Pfizer.co.uk where you will be able to access reference information on Pfizer's prescription medicines.
*The ABPI Code definition for healthcare professional is members of the medical, dental, pharmacy and nursing professionals and any other persons who in the course of their professional activities may administer, prescribe, purchase, recommend or supply a medicine.
PP-PFE-GBR-3863. November 2021
OK, We will need you to sign in before we can determine if you are aligned with a Pﬁzer promotional colleague.This is an interstitial message to prompt a HCP before they login.
If you have already registered with pfizerpro.co.uk and select ‘yes’, you will be directed to the sign-in page where you will be required to enter your username and password.
Would you like to register or sign in now?