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Adverse event reporting can be found at the bottom of the page
About
Mode of Action
Ritlecitinib irreversibly and selectively inhibits JAK3 and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family by blocking the adenosine triphosphate (ATP) binding site.1
In cellular settings, ritlecitinib specifically inhibits γ-common cytokines (IL-2, IL-4, IL-7, IL-15 and IL-21) signalling through JAK3-dependent common-γ chain receptors.1
Additionally, ritlecitinib inhibits TEC family of kinases, resulting in reduced cytolytic activity of NK cells and CD8+ T cells.1
LITFULO 50mg
One Strength,
One Capsule,
Once Daily1
Read about Getting Started
See our efficacy profile including SALT evaluation examples and eyebrow and eyelash responses
Learn about Efficacy
Read about our Safety profile including Safety Considerations and Adverse Reactions
See the Safety Profile
CD= cluster of differentiation, IL=interleukin, JAK=janus kinase, NK=natural killer
References:
Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk or search
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Adverse events should also be reported to Pfizer Medical Information on 01304 616161
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